Dihydroergotoxine mesylate
Dihydroergotoxine mesylate structure
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Common Name | Dihydroergotoxine mesylate | ||
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| CAS Number | 8067-24-1 | Molecular Weight | 2314.74 | |
| Density | 1.34g/cm3 | Boiling Point | 899.5ºC at 760 mmHg | |
| Molecular Formula | C123H156N20O23S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 497.8ºC | |
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Pharmacological treatments of cerebellar ataxia.
Cerebellum 3(2) , 107-11, (2004) The confirmed pharmacological treatment of cerebellar ataxia is still lacking. In a recent preliminary trial, we showed that D-cycloserine, a partial NMDA allosteric agonist, may relieve the symptoms. In this paper, major clinical trials to relieve ataxic sym... |
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Cerebroprotective drugs shorten the hypoxia-induced onset of electrical silence in unanesthetized rats.
Pharmacol. Res. 42(3) , 261-8, (2000) Pharmacological agents that delay the hypoxic arrest of neuronal electrical activity, as indicated by the suppression of electroencephalogram (EEG), have previously been thought to increase brain resistance to oxygen insufficiency. On the other hand, accelera... |
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Identification and human pharmacokinetics of dihydroergotoxine metabolites in man: preliminary results.
Biopharm. Drug Dispos. 29(1) , 17-28, (2008) Dihydroergotoxine is a mixture of semi-synthetic ergot alkaloids mainly used for age-related cognitive impairment. In this study, dihydroergotoxine (30 microM) was added to incubates of rat and bovine liver microsomes, and the resulting major metabolites were... |
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Alpha-dihydroergocryptine and predictive factors in migraine prophylaxis.
Int. J. Clin. Pharmacol. Ther. 39(4) , 144-51, (2001) A double-blind, crossover study was carried out to compare the efficacy of alpha-dihydroergocryptine mesylate (10 mg twice daily) vs propranolol (40 mg twice daily) in the prophylaxis of migraine without aura, and to identify possible predictors of therapeuti... |
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Age, strain, and semi-chronic hydergine treatment effects on motor activity and neuronal nucleic acid-protein metabolism in male mice.
Life Sci. 67(12) , 1489-505, (2000) This study was designed to examine the effects of Hydergine (DHET), co-dergocrine mesylate, treatment on motor activity and neuronal nucleoprotein metabolism in several motor areas of the aging rodent brain, specifically the caudate-putamen (CP), the substant... |
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Dopamine agonist therapy for hyperprolactinemia.
Clin. Obstet. Gynecol. 46(2) , 349-62, (2003)
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The effect of topically applied vasoactive agents and testosterone versus testosterone in the treatment of erectile dysfunction in aged men with low sexual interest.
Int. J. Impot. Res. 13(2) , 93-9, (2001) The objective was to evaluate the efficacy and safety of topically applied cream containing testosterone, isosorbide dinitrate and co-dergocrine mesylate compared to testosterone cream in the treatment of erectile dysfunction in aged men with low sexual inter... |
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[Redergin treatment of hypertensive menopausal women].
Ter. Arkh. 72(11) , 47-50, (2000) To assess a hypotensive effect of redergin (dihydroergotoxin)--agonist of dopaminergic receptors--in monotherapy (4.5-6 mg/day) and in combination with enalapril and amlodipin (10 mg/day).Redergin in monotherapy or combined therapy was given to 106 hypertensi... |
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[Can a hydergine therapy lead to damage of the coronary vessels?].
Dtsch. Med. Wochenschr. 127(25-26) , 1401, (2002)
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Featured CME topic: dementia. Medication update.
South. Med. J. 94(7) , 678-81, (2001)
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