GW7647
GW7647 structure
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Common Name | GW7647 | ||
|---|---|---|---|---|
| CAS Number | 265129-71-3 | Molecular Weight | 502.752 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 693.9±55.0 °C at 760 mmHg | |
| Molecular Formula | C29H46N2O3S | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 373.5±31.5 °C | |
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Activation of PPAR gamma receptors reduces levodopa-induced dyskinesias in 6-OHDA-lesioned rats.
Neurobiol. Dis. 74 , 295-304, (2015) Long-term administration of l-3,4-dihydroxyphenylalanine (levodopa), the mainstay treatment for Parkinson's disease (PD), is accompanied by fluctuations in its duration of action and motor complications (dyskinesia) that dramatically affect the quality of lif... |
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A role for oleoylethanolamide in chronic lymphocytic leukemia.
Leukemia 28(7) , 1381-7, (2014) Oleoylethanolamide (OEA) is a bioactive lipid that stimulates nuclear and G protein-coupled receptors and regulates appetite and fat metabolism. It has not previously been shown to have a role in cancer. However, a mass spectrometry-based lipidomics platform ... |
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Expression of 15-Hydroxyprostaglandin Dehydrogenase in Human Chorion Is Associated with Peroxisome Proliferator-Activated Receptor Isoform Expression in Term Labor.
Am. J. Pathol. 185 , 1981-90, (2015) Chorionic NAD-dependent 15-hydroxy prostaglandin dehydrogenase (PGDH) plays a pivotal role in controlling the amount of prostaglandins in the uterus. Peroxisome proliferator-activated receptors (PPARs) are implicated to be involved in parturition. In this stu... |
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CIDEC/FSP27 is regulated by peroxisome proliferator-activated receptor alpha and plays a critical role in fasting- and diet-induced hepatosteatosis.
Hepatology 61(4) , 1227-38, (2015) The cell death-inducing DNA fragmentation factor alpha-like effector c (CIDEC; also known in rodents as FSP27 or fat-specific protein 27) is a lipid droplet-associated protein that promotes intracellular triglyceride (TAG) storage. CIDEC/Fsp27 is highly expre... |
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Glucagon stimulates hepatic FGF21 secretion through a PKA- and EPAC-dependent posttranscriptional mechanism.
PLoS ONE 9(4) , e94996, (2014) Previous studies have shown that whole body deletion of the glucagon receptor suppresses the ability of starvation to increase hepatic fibroblast growth factor 21 (FGF21) expression and plasma FGF21 concentration. Here, we investigate the mechanism by which g... |
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Lipidomics identifies a requirement for peroxisomal function during influenza virus replication.
J. Lipid Res. 55(7) , 1357-1365, (2014) Influenza virus acquires a host-derived lipid envelope during budding, yet a convergent view on the role of host lipid metabolism during infection is lacking. Using a mass spectrometry-based lipidomics approach, we provide a systems-scale perspective on membr... |