CP 55,940
CP 55,940 structure
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Common Name | CP 55,940 | ||
|---|---|---|---|---|
| CAS Number | 83002-04-4 | Molecular Weight | 376.573 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 494.4±45.0 °C at 760 mmHg | |
| Molecular Formula | C24H40O3 | Melting Point | N/A | |
| MSDS | USA | Flash Point | 209.2±23.3 °C | |
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Impact of efficacy at the μ-opioid receptor on antinociceptive effects of combinations of μ-opioid receptor agonists and cannabinoid receptor agonists.
J. Pharmacol. Exp. Ther. 351(2) , 383-9, (2014) Cannabinoid receptor agonists, such as Δ(9)-tetrahydrocannabinol (Δ(9)-THC), enhance the antinociceptive effects of μ-opioid receptor agonists, which suggests that combining cannabinoids with opioids would improve pain treatment. Combinations with lower effic... |
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Essential role for STIM1/Orai1-mediated calcium influx in PDGF-induced smooth muscle migration.
Am. J. Pathol. 298 , C993-1005, (2010) We recently demonstrated that thapsigargin-induced passive store depletion activates Ca(2+) entry in vascular smooth muscle cells (VSMC) through stromal interaction molecule 1 (STIM1)/Orai1, independently of transient receptor potential canonical (TRPC) chann... |
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Characterizing cannabinoid CB2 receptor ligands using DiscoveRx PathHunter beta-arrestin assay.
J. Biomol. Screen. 14 , 49-58, (2009) The authors have characterized a set of cannabinoid CB(2) receptor ligands, including triaryl bis sulfone inverse agonists, in a cell-based receptor/beta-arrestin interaction assay (DiscoveRx PathHunter). The results were compared with results using a competi... |
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Possible contribution of pannexin channel to ATP-induced currents in vitro in vasopressin neurons isolated from the rat supraoptic nucleus
Brain Res. 1394 , 71-8, (2011) Release of arginine vasopressin (AVP) from magnocellular neurosecretory cells (MNCs) of the supraoptic nucleus (SON) is controlled by the electrical activity of these neurons. ATP plays a crucial role in the regulation of SON MNCs by activating the purinergic... |