d-arabinose 5-phosphate disodium salt

d-arabinose 5-phosphate disodium salt Structure
d-arabinose 5-phosphate disodium salt structure
Common Name d-arabinose 5-phosphate disodium salt
CAS Number 89927-09-3 Molecular Weight 274.07300
Density N/A Boiling Point N/A
Molecular Formula C5H9Na2O8P Melting Point N/A
MSDS Chinese USA Flash Point N/A

Escherichia coli YrbH is a D-arabinose 5-phosphate isomerase.

J. Biol. Chem. 278 , 32771-32777, (2003)

A gene encoding for arabinose 5-phosphate isomerase (API), which catalyzes the interconversion of d-ribulose 5-phosphate (Ru5P) and d-arabinose 5-phosphate (A5P), has been identified from the genome of Escherichia coli K-12. API is the first enzyme in the bio...

Probing the active site of the sugar isomerase domain from E. coli arabinose-5-phosphate isomerase via X-ray crystallography.

Protein Sci. 19 , 2430-2439, (2010)

Lipopolysaccharide (LPS) biosynthesis represents an underexploited target pathway for novel antimicrobial development to combat the emergence of multidrug-resistant bacteria. A key player in LPS synthesis is the enzyme D-arabinose-5-phosphate isomerase (API),...

Enediol mimics as inhibitors of the D-arabinose 5-phosphate isomerase (KdsD) from Francisella tularensis.

Bioorg. Med. Chem. Lett. 21 , 2679-2682, (2011)

We explored the D-arabinose 5-phosphate isomerase (KdsD, E.C. 5.3.1.13) from Francisella tularensis, a highly infectious gram-negative pathogen that has raised concern as a potential bioweapon, as a target for the development of novel chemotherapeutics. F. tu...

Targeting the role of a key conserved motif for substrate selection and catalysis by 3-deoxy-D-manno-octulosonate 8-phosphate synthase.

Biochemistry 50 , 3686-3695, (2011)

3-Deoxy-D-manno-octulosonate 8-phosphate synthase (KDO8PS) catalyzes the reaction between three-carbon phosphoenolpyruvate (PEP) and five-carbon d-arabinose 5-phosphate (A5P), generating KDO8P, a key intermediate in the biosynthetic pathway to 3-deoxy-D-manno...