![]() Benzo[h]quinoline structure
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Common Name | Benzo[h]quinoline | ||
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CAS Number | 230-27-3 | Molecular Weight | 179.217 | |
Density | 1.2±0.1 g/cm3 | Boiling Point | 340.8±0.0 °C at 760 mmHg | |
Molecular Formula | C13H9N | Melting Point | 48-50 °C(lit.) | |
MSDS | Chinese USA | Flash Point | 155.9±11.9 °C |
Synthesis of novel benzo[h]quinolines: Wound healing, antibacterial, DNA binding and in vitro antioxidant activity
Eur. J. Med. Chem. 44 , 981-9, (2009) We have characterized a new class of 2-mercapto/2-selenobenzo[ h]quinoline-3-carbaldehyde ( 3/ 4). Antibacterial potential of these compounds against a wide range of Gram-positive and Gram-negative bacteria was studied. The selenium containing compound 4 show... |
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Determination of basic nitrogen-containing polynuclear aromatic hydrocarbons formed during thermal degradation of polymers by high-performance liquid chromatography-fluorescence detection.
J. Chromatogr. A. 878(2) , 171-81, (2000) A method for the simultaneous determination of 22 nitrogen-containing polynuclear aromatic hydrocarbons (PAHs) (15 azaarenes and seven amino-PAHs) in the gaseous products of the thermal degradation of polymers is described. After desorption and clean-up using... |
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Mutagenicity and tumorigenicity of dihydrodiols, diol epoxides, and other derivatives of benzo(f)quinoline and benzo(h)quinoline.
Cancer Res. 49(1) , 20-4, (1989) The mutagenic activities of benzo[f]quinoline, benzo[h]quinoline, and a number of their derivatives, including dihydrodiols, K-region oxides, diol epoxides, and tetrahydroepoxides, were assessed in strain TA 100 of Salmonella typhimurium. The dihydrodiol deri... |
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In vivo mutagenicity of benzo[f]quinoline, benzo[h]quinoline, and 1,7-phenanthroline using the lacZ transgenic mice.
Mutat. Res. 559(1-2) , 83-95, (2004) Phenanthrene, a simplest angular polycyclic aromatic hydrocarbon with a bay-region in its molecule, is reported to be non-mutagenic, although most angular (non-linear) polycyclic aromatic hydrocarbons, such as benzo[a]pyrene and chrysene, are known to show ge... |
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Crowded Cu(I) complexes involving benzo[h]quinoline: pi-stacking effects and long-lives excited states.
Inorg. Chem. 40(14) , 3413-22, (2001) The Friedländer condensation was employed to synthesize two series of 3,3'-polymethylene bridged ligands, L, based on 2-(2'-pyridyl)-benzo[h]quinoline and 2,2'-bibenzo[h]quinoline (BHQ) along with the fully aromatic naphtho[1,2-b]-1,10-phenanthroline. Complex... |
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The carcinogenicity of quinoline and benzoquinolines in newborn CD-1 mice.
Jpn. J. Cancer Res. 78(2) , 139-43, (1987) The environmental occurrence and mutagenic activity of quinoline and benzoquinolines are well-documented. In this study, the relative carcinogenic activities of quinoline, benzo[f]quinoline, benzo[h]quinoline, and phenanthridine were evaluated in newborn mice... |
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Identification of the metabolites of benzo[f]quinoline and benzo[h]quinoline formed by rat liver homogenate.
Carcinogenesis 4(9) , 1133-8, (1983) Benzo[f]quinoline and benzo[h]quinoline are widespread environmental pollutants which have been found to be mutagenic. The metabolism of benzo[f]quinoline and benzo[h]quinoline was investigated using a liver homogenate from Aroclor-pretreated rats. The metabo... |
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pH dependence of binding benzo[h]quinoline and humic acid and effects on fluorescence quenching.
Environ. Toxicol. Chem. 29(8) , 1696-702, (2010) The binding constant (K(DOC)) between humic acid and the nitrogen-containing polycyclic aromatic compound (N-PAC), benzo[h]quinoline, was measured at varying pH levels using fluorescence quenching (FQ). Because fluorescence characteristics of benzo[h]quinolin... |
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Fungal biotransformation of benzo[f]quinoline, benzo[h]quinoline, and phenanthridine.
Appl. Microbiol. Biotechnol. 67(3) , 405-11, (2005) Cultures of Umbelopsis ramanniana (=Mucor ramannianus) were grown in fluid Sabouraud medium for 3 days, dosed with 0.23 mM benzo[f]quinoline, benzo[h]quinoline, or phenanthridine (benzo[c]quinoline), and incubated for another 18 days. Cultures were extracted ... |
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Synthesis of sterically encumbered C10-arylated benzo[h]quinolines using ortho-substituted aryl boronic acids.
Org. Biomol. Chem. 11(1) , 31-4, (2013) The challenging coupling of 10-halobenzo[h]quinolines with ortho-substituted aryl boronic acids has been achieved using Pd(OAc)(2)/P(O)Ph(3) as the catalytic system. High yields were obtained for diversely functionalised substrates under mild reaction conditi... |