1-Methylurea
1-Methylurea structure
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Common Name | 1-Methylurea | ||
|---|---|---|---|---|
| CAS Number | 598-50-5 | Molecular Weight | 74.082 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 114.6±13.0 °C at 760 mmHg | |
| Molecular Formula | C2H6N2O | Melting Point | ~93 °C | |
| MSDS | Chinese USA | Flash Point | 23.1±19.8 °C | |
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The FGFR Inhibitor NVP-BGJ398 Induces NSCLC Cell Death by Activating Caspase-dependent Pathways as well as Caspase-independent Apoptosis.
Anticancer Res. 35 , 5873-9, (2015) Fibroblast growth factor receptors are expressed in diverse cell types. They play a critical role in tumor development. Their activation promotes cell-cycle progression, angiogenesis, and cell survival by induction/suppression of the expression of proteins in... |
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Characteristics of urea transport of cells derived from rabbit thick ascending limb of Henle's loop.
Kidney Int. 54(1) , 152-9, (1998) The thick ascending limb of Henle's loop (TALH) is thought to be involved in the regulation of the renal urea gradient.We have characterized the uptake of urea (oil density centrifugation and 2-compartment-culture) and volume regulation (impedance measurement... |
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[Derivatives of antineoplastic antibiotics of the daunorubicin series containing methylurea or nitrosomethylurea residues].
Bioorg. Khim. 16(4) , 559-68, (1990) Derivatives of antitumour anthracycline antibiotics containing N-methylurea moiety in the carbohydrate ring were obtained by the interaction of methyl isocyanate with daunorubicin, doxorubicin, carminomycin and daunorubicin derivatives, substituted at C-13 or... |
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Solvation of human serum albumin in aqueous alkylurea solutions.
Int. J. Pept. Protein Res. 42(4) , 320-5, (1993) Solvation of human serum albumin in aqueous solutions of urea, methyl-, N,N'-dimethyl-, and ethylurea was studied by density measurements. From the densities at constant molality and constant chemical potential, the preferential solvation parameters of human ... |
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[Changes in the adhesiveness between enterocytes after short-term blastomogenic exposures].
Tsitologiia 31(12) , 1459-65, (1989) Following short-term local applications of high doses of N-methyl-N-nitrozourea and 7,2-dimethylbenz(a)antracen, the intercellular adhesion in the distal colon epithelium of ice retains increased at least for a month. The magnitude of this shift and its durat... |
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Effect of physiological concentration of urea on the conformation of human serum albumin.
J. Biochem. 141(2) , 261-8, (2007) We report that the presence of very low concentrations (<0.1 M) of urea, a widely used chemical denaturant, induces structure formation in the water-soluble globular protein human serum albumin (HSA) at pH 7. We have presented results suggesting an almost 8% ... |
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Antimutagenic effect of one variety of green pepper (Capsicum spp.) and its possible interference with the nitrosation process.
Mutat. Res. 496(1-2) , 39-45, (2001) It is known that the poblano green pepper, a significant component in the Mexican diet, contains certain natural compounds such as chlorophyll, beta-carotene, and vitamins, which have antimutagenic and/or anticarcinogenic properties. Using the somatic mutatio... |
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Deuterium isotope effect on the toxicokinetics of monomethylamine in the rat.
Drug Metab. Dispos. 18(4) , 447-52, (1990) The single-dose toxicokinetics of monomethylamine has been characterized in the rat by HPLC assay of serial blood samples. Biphasic first-order elimination was observed following an iv bolus dose of 19 mumol/kg with a terminal half-life of 19.1 +/- 1.3 min (m... |
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Analysis of the in vivo nitrosation capacity of the larvae used in the wing somatic mutation and recombination test of Drosophila melanogaster.
Mutat. Res. 412(1) , 69-81, (1998) The in vivo nitrosation capacity of third-instar larvae of Drosophila melanogaster was assessed using the wing somatic mutation and recombination test (SMART). Larvate derived from two different crosses, the standard cross (ST) and the high bioactivation cros... |
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Single water channels of aquaporin-1 do not obey the Kedem-Katchalsky equations.
J. Membr. Biol. 181(2) , 115-23, (2001) The Kedem-Katchalsky (KK) equations are often used to obtain information about the osmotic properties and conductance of channels to water. Using human red cell membranes, in which the osmotic flow is dominated by Aquaporin-1, we show here that compared to Na... |