lyso-ganglioside gm1, bovine
lyso-ganglioside gm1, bovine structure
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Common Name | lyso-ganglioside gm1, bovine | ||
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| CAS Number | 171483-40-2 | Molecular Weight | 1297.39000 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C55H100N4O30 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
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Lysosphingolipids inhibit protein kinase C: implications for the sphingolipidoses.
Science 235 , 670, (1987) Lysosphingolipids potently and reversibly inhibited protein kinase C activity and binding of phorbol dibutyrate in vitro and in human platelets. As with activation of protein kinase C by phosphatidylserine and sn-1,2-diacylglycerol, inhibition was subject to ... |
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Accumulation of lysosphingolipids in tissues from patients with GM1 and GM2 gangliosidoses.
J. Neurochem. 59 , 1452, (1992) By using a sensitive method, we assayed lysocompounds of gangliosides and asialogangliosides in tissues from four patients with GM2 gangliosidosis (one with Sandhoff disease and three with Tay-Sachs disease) and from three patients with GM1 gangliosidosis [on... |
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LIGA20, a lyso derivative of ganglioside GM1, given orally after cortical thrombosis reduces infarct size and associated cognition deficit.
Proc. Natl. Acad. Sci. U. S. A. 91 , 6303, (1994) A bilateral photochemically induced thrombotic lesion of rat sensorimotor cortex (approximately 3 mm in diameter and 25 mm3 in volume) is associated with a persistent cognition (learning and memory) deficit, which was evaluated with water maze tasks. The N-di... |
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Cellular incorporation and localization of fluorescent derivatives of gangliosides, cerebroside and sphingomyelin.
FEBS Lett. 281 , 39, (1991) Fluorescent dansyl derivatives of 3 natural sphingolipids (gangliosides, cerebroside and sphingomyelin) were shown to be readily taken up by culture cells (HeLa-, MDCK- and primary rat brain cells). A part of the incorporated fluorescent sphingolipids remaine... |
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Tubaro, E., et al.
Eur. J. Pharmacol. Environ. Toxicol. Pharmacol. Soc. 248 , 175, (1993)
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