sphingomyelin

sphingomyelin Structure
sphingomyelin structure
Common Name sphingomyelin
CAS Number 85187-10-6 Molecular Weight 732.08
Density N/A Boiling Point N/A
Molecular Formula C41H84N2O6P Melting Point N/A
MSDS Chinese USA Flash Point N/A

Sphingomyelin depletion impairs anionic phospholipid inward translocation and induces cholesterol efflux.

J. Biol. Chem. 288(52) , 37166-79, (2013)

The phosphatidylserine (PS) floppase activity (outward translocation) of ABCA1 leads to plasma membrane remodeling that plays a role in lipid efflux to apolipoprotein A-I (apoAI) generating nascent high density lipoprotein. The Tangier disease W590S ABCA1 mut...

Characterization of freeze-fractured epithelial plasma membranes on nanometer scale with ToF-SIMS.

Anal. Bioanal. Chem , (2014)

Time-of-flight secondary ion mass spectrometry (ToF-SIMS) was used to characterize the freeze-fracturing process of human epithelial PANC-1 and UROtsa cells. For this purpose, phosphatidylcholine, sphingomyelin, phosphatidylethanolamine, and phosphatidylserin...

Binding of vascular anticoagulant alpha (VAC alpha) to planar phospholipid bilayers.

J. Biol. Chem. 265(9) , 4923-8, (1990)

Vascular anticoagulant alpha (VAC alpha, annexin V) is a member of the family of calcium and phospholipid binding proteins, the annexins. The binding properties of VAC alpha to phospholipid bilayers were studied by ellipsometry. Adsorption was calcium-depende...

A calibrated fluorescence polarization assay for assessment of fetal lung maturity.

Clin. Chem. 33(7) , 1177-84, (1987)

The mechanism of a new fluorescence polarization method for measuring phospholipid in amniotic fluid is described. The fluorescence polarization of a surfactant fluorescent dye solubilized in amniotic fluid correlates significantly with the L/S ratio. Model s...

Rapid, specific, and sensitive measurements of plasma sphingomyelin and phosphatidylcholine.

J. Lipid Res. 47(3) , 673-6, (2006)

Sphingomyelin (SM) and phosphatidylcholine (PC) are two major phospholipids on plasma lipoproteins. Their concentration is classically measured by lipid extraction, thin-layer chromatography, and phosphate determination on separated SM or PC spots. Here, we d...

Definitive assignment of proton selectivity and attoampere unitary current to the M2 ion channel protein of influenza A virus.

J. Virol. 75(8) , 3647-56, (2001)

The viral ion channel protein M2 supports the transit of influenza virus and its glycoproteins through acidic compartments of the cell. M2 conducts endosomal protons into the virion to initiate uncoating and, by equilibrating the pH at trans-Golgi membranes, ...

Rational basis for foam-stability assays of amniotic fluid surfactant.

Clin. Chem. 24(11) , 1980-4, (1978)

We evaluated the relative contributions of various phospholipids to the formation of foam in the amniotic fluid "foam stability test", by use of an artificial system of saline, ethanol, and dipalmitoyl 3-sn-phosphatidylcholine to determine the relationship be...

Biological functions of sphingomyelins. Slotte JP.

Prog. Lipid Res. 52(4) , 424-437, (2013)