Erythropoietin
Erythropoietin structure
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Common Name | Erythropoietin | ||
|---|---|---|---|---|
| CAS Number | 11096-26-7 | Molecular Weight | 3025.49000 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C134H226N38O41 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
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Amelioration of radiation-induced oral cavity mucositis and distant bone marrow suppression in fanconi anemia Fancd2-/- (FVB/N) mice by intraoral GS-nitroxide JP4-039.
Radiat. Res. 182(1) , 35-49, (2014) The altered DNA damage response pathway in patients with Fanconi anemia (FA) may increase the toxicity of clinical radiotherapy. We quantitated oral cavity mucositis in irradiated Fanconi anemia Fancd2(-/-) mice, comparing this to Fancd2(+/-) and Fancd2(+/+) ... |
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The alternative splicing factor Nova2 regulates vascular development and lumen formation.
Nat. Commun. 6 , 8479, (2015) Vascular lumen formation is a fundamental step during angiogenesis; yet, the molecular mechanisms underlying this process are poorly understood. Recent studies have shown that neural and vascular systems share common anatomical, functional and molecular simil... |
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Recombinant human erythropoietin to target cognitive dysfunction in bipolar disorder: a double-blind, randomized, placebo-controlled phase 2 trial.
J. Clin. Psychiatry 75(12) , 1347-55, (2014) Available drug treatments for bipolar disorder fail to reverse patients' cognitive deficits. Erythropoietin has neurotrophic actions and aids neurocognitive function. The aim of the study was to investigate the potential of erythropoietin to treat cognitive d... |
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Co-stimulation with stem cell factor and erythropoietin enhances migration of c-Kit expressing cervical cancer cells through the sustained activation of ERK1/2.
Mol. Med. Report. 9(5) , 1895-902, (2014) The cytokines erythropoietin (Epo) and stem cell factor (SCF), coupled with the cooperation between their receptors (EpoR and c-Kit), are essential components of normal physiological erythropoiesis. In earlier studies, we demonstrated the expression of c-Kit ... |
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Avoiding unnecessary blood transfusions in women with profound anaemia.
Aust. N. Z. J. Obstet. Gynaecol. 55 , 262-7, (2015) Blood transfusions may be associated with risks and the risk: benefit ratio is not always clear, even in the setting of haemorrhage.To describe the management practices and outcomes in women with profound anaemia who refused blood transfusion.Retrospective an... |
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Nonmarrow hematopoiesis occurs in a hyaluronic-acid-rich node and duct system in mice.
Stem Cells Dev. 23(21) , 2661-71, (2014) A hyaluronic-acid-rich node and duct system (HAR-NDS) was found on the surface of internal organs of mice, and inside their blood and lymph vessels. The nodes (HAR-Ns) were filled with immune cells of the innate system and were especially enriched with mast c... |
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Ribosomal protein L11- and retinol dehydrogenase 11-induced erythroid proliferation without erythropoietin in UT-7/Epo erythroleukemic cells.
Exp. Hematol. 43 , 414-423.e1, (2015) Erythropoiesis is the process of proliferation, differentiation, and maturation of erythroid cells. Understanding these steps will help to elucidate the basis of specific diseases associated with abnormal production of red blood cells. In this study, we conti... |
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Epoetin Alpha and Epoetin Zeta: A Comparative Study on Stimulation of Angiogenesis and Wound Repair in an Experimental Model of Burn Injury.
Biomed Res. Int. 2015 , 968927, (2015) Deep second-degree burns are characterized by delayed formation of granulation tissue and impaired angiogenesis. Erythropoietin (EPO) is able to stimulate angiogenesis and mitosis, activating vascularization and cell cycle. The aim of our study was to investi... |
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Isolation and transcriptome analyses of human erythroid progenitors: BFU-E and CFU-E.
Blood 124(24) , 3636-45, (2014) Burst-forming unit-erythroid (BFU-E) and colony-forming unit-erythroid (CFU-E) cells are erythroid progenitors traditionally defined by colony assays. We developed a flow cytometry-based strategy for isolating human BFU-E and CFU-E cells based on the changes ... |
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Lysophosphatidic acid enhances survival of human CD34(+) cells in ischemic conditions.
Sci. Rep. 5 , 16406, (2015) Several clinical trials are exploring therapeutic effect of human CD34(+) cells in ischemic diseases, including myocardial infarction. Unfortunately, most of the cells die few days after delivery. Herein we show that lysophosphatidic acid (LPA)-treated human ... |