Indapamide
Indapamide structure
|
Common Name | Indapamide | ||
|---|---|---|---|---|
| CAS Number | 26807-65-8 | Molecular Weight | 365.835 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C16H16ClN3O3S | Melting Point | 160-162°C | |
| MSDS | Chinese USA | Flash Point | N/A | |
|
cIEF for rapid pKa determination of small molecules: a proof of concept.
Eur. J. Pharm. Sci. 63 , 14-21, (2014) A capillary isoelectric focusing (cIEF) method was developed for the determination of the ionization constants (pKa) of small molecules. Two approaches used to decrease the electroosmotic flow (EOF) were compared: (i) a hydroxypropylcellulose (HPC) coated cap... |
|
|
Prevalence of hyponatremia among patients who used indapamide and hydrochlorothiazide: a single center retrospective study.
Saudi J. Kidney Dis. Transpl. 24(2) , 281-5, (2013) Hyponatremia is the most frequently encountered electrolyte abnormality among hospitalized patients and thiazide users. In this large single-center retrospective study, we aim to determine the prevalence and risk factors of hyponatremia among patients at the ... |
|
|
Fast targeted analysis of 132 acidic and neutral drugs and poisons in whole blood using LC-MS/MS.
Forensic Sci. Int. 243 , 35-43, (2014) The aim of this study was to develop an LC-MS/MS based screening technique that covers a broad range of acidic and neutral drugs and poisons by combining a small sample volume and efficient extraction technique with simple automated data processing. After pro... |
|
|
Ultra high performance supercritical fluid chromatography coupled with tandem mass spectrometry for screening of doping agents. I: Investigation of mobile phase and MS conditions.
Anal. Chim. Acta 853 , 637-46, (2014) The conditions for the analysis of selected doping substances by UHPSFC-MS/MS were optimized to ensure suitable peak shapes and maximized MS responses. A representative mixture of 31 acidic and basic doping agents was analyzed, in both ESI+ and ESI- modes. Th... |
|
|
Ultra high performance supercritical fluid chromatography coupled with tandem mass spectrometry for screening of doping agents. II: Analysis of biological samples.
Anal. Chim. Acta 853 , 647-59, (2014) The potential and applicability of UHPSFC-MS/MS for anti-doping screening in urine samples were tested for the first time. For this purpose, a group of 110 doping agents with diverse physicochemical properties was analyzed using two separation techniques, nam... |
|
|
Predicting the effects of blood pressure-lowering treatment on major cardiovascular events for individual patients with type 2 diabetes mellitus: results from Action in Diabetes and Vascular Disease: Preterax and Diamicron MR Controlled Evaluation.
Hypertension 65(1) , 115-21, (2015) Blood pressure-lowering treatment reduces cardiovascular risk in patients with diabetes mellitus, but the effect varies between individuals. We sought to identify which patients benefit most from such treatment in a large clinical trial in type 2 diabetes mel... |
|
|
Solid-state compatibility screening of excipients suitable for development of indapamide sustained release solid-dosage formulation.
Pharm. Dev. Technol. 18(2) , 481-9, (2013) Differential scanning calorimetry and Fourier transform infrared spectroscopy were applied as screening analytical methods to assess the solid-state compatibility of indapamide (4-chloro-N-(2-methyl-2,3-dihydroindol-1-yl)-3-sulfamoyl-benzamide) with several p... |
|
|
[Vascular effects of perindopril arginine and indapamide fixed combination in patients with arterial hypertension].
Kardiologiia 52(9) , 8-14, (2012) The aim of the study was to investigate the dynamics of arterial stiffness and endothelial function parameters under the influence of perindopril arginine and indapamide fixed combination in arterial hypertension (AH) patients. 30 persons with 1-3 degree AH w... |
|
|
[Nephroprotection diabetes mellitus type 2: lessons from the ADVANCE trial].
Kardiologiia 51(12) , 57-9, (2011) Based on the results of the ADVANCE study, the article considers the issues of medication nephroprotection in patients with type 2 diabetes mellitus, including patients with uncontrolled arterial hypertension. Potentials for use of fixed combination of perind... |
|
|
Evidence-based triple antihypertensive therapy yields lower mortality in older patients with diabetes mellitus.
Hypertension 63(2) , 220-1, (2014)
|