(3H-Imidazol-4-yl)-acetic acid HCl
(3H-Imidazol-4-yl)-acetic acid HCl structure
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Common Name | (3H-Imidazol-4-yl)-acetic acid HCl | ||
|---|---|---|---|---|
| CAS Number | 3251-69-2 | Molecular Weight | 162.574 | |
| Density | 1.426g/cm3 | Boiling Point | 447.3ºC at 760mmHg | |
| Molecular Formula | C5H7ClN2O2 | Melting Point | 218-222 °C(lit.) | |
| MSDS | USA | Flash Point | 224.3ºC | |
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Chemical genetics reveals a complex functional ground state of neural stem cells.
Nat. Chem. Biol. 3(5) , 268-273, (2007) The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain cancer. However, the complete repertoire of signaling pathways ... |
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Highly sensitive and specific detection of histamine via the formation of a self-assembled magic number cluster with thymine by mass spectrometry.
Analyst 139(12) , 3154-9, (2014) A novel method for the detection of histamine (HIM) via the formation of a self-assembled magic number cluster with thymine (T) by electrospray ionization tandem mass spectrometry (ESI-MS/MS) is described. The formation of the magic number cluster [T17 + HIM ... |
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Cross-talk between GlcNAcylation and phosphorylation: site-specific phosphorylation dynamics in response to globally elevated O-GlcNAc.
Proc. Natl. Acad. Sci. U. S. A. 105(37) , 13793-8, (2008) Protein GlcNAcylation serves as a nutrient/stress sensor to modulate the functions of many nuclear and cytoplasmic proteins. O-GlcNAc cycles on serine or threonine residues like phosphorylation, is nearly as abundant, and functions, at least partially, via it... |
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Rat alpha6beta2delta GABAA receptors exhibit two distinct and separable agonist affinities.
J. Physiol. 581(Pt 3) , 1001-18, (2007) The onset of motor learning in rats coincides with exclusive expression of GABAA receptors containing alpha6 and delta subunits in the granule neurons of the cerebellum. This development temporally correlates with the presence of a spontaneously active chlori... |
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Enhanced phosphopeptide isolation by Fe(III)-IMAC using 1,1,1,3,3,3-hexafluoroisopropanol.
Proteomics 5(17) , 4376-88, (2005) IMAC can be used to selectively enrich phosphopeptides from complex peptide mixtures, but co-retention of acidic peptides together with the failure to retain some phosphopeptides restricts the general utility of the method. In this study Fe(III)-IMAC was qual... |
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Kinetic analysis of the role of histidine chloramines in hypochlorous acid mediated protein oxidation.
Biochemistry 44(19) , 7378-87, (2005) Hypochlorous acid (HOCl) is a powerful oxidant generated from H(2)O(2) and chloride ions by the heme enzyme myeloperoxidase (MPO) released from activated leukocytes. In addition to its potent antibacterial effects, excessive HOCl production can lead to host t... |
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Peripheral GABAB agonists stimulate gastric acid secretion in mice.
Br. J. Pharmacol. 142(6) , 1038-48, (2004) 1 We characterized the effects of intravenous GABA and preferential GABAA (muscimol), GABAB (R-baclofen and SKF-97541) and GABAC agonists (imidazole-4-acetic acid) on gastric acid secretion in urethane-anesthetized mice implanted with a gastric cannula, and d... |
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Theoretical studies of IMAC interfacial phenomena for the production of protein C.
Adv. Exp. Med. Biol. 540 , 183-90, (2003)
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Characterization of phosphorylation sites on Tpl2 using IMAC enrichment and a linear ion trap mass spectrometer.
J. Proteome Res. 6(6) , 2269-76, (2007) Advances in analytical techniques, specifically in mass spectrometry, have allowed for both facile protein identification and routine sequencing of proteins at increased sensitivity levels. Protein modifications present additional challenges because they occu... |
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Identification of a tyrosine in the agonist binding site of the homomeric rho1 gamma-aminobutyric acid (GABA) receptor that, when mutated, produces spontaneous opening.
J. Biol. Chem. 277(46) , 43741-8, (2002) Mutagenesis of recombinant rho1 gamma-aminobutyric acid (GABA) receptors has previously identified five residues in the amino terminal extracellular domain that play an important role in GABA binding. Here, we present evidence that the tyrosine at position 10... |