2-O-METHYL-ALPHA-D-N-ACETYLNEURAMINIC ACID

2-O-METHYL-ALPHA-D-N-ACETYLNEURAMINIC ACID Structure
2-O-METHYL-ALPHA-D-N-ACETYLNEURAMINIC ACID structure
Common Name 2-O-METHYL-ALPHA-D-N-ACETYLNEURAMINIC ACID
CAS Number 50930-22-8 Molecular Weight 323.296
Density 1.5±0.1 g/cm3 Boiling Point 732.6±60.0 °C at 760 mmHg
Molecular Formula C12H21NO9 Melting Point N/A
MSDS USA Flash Point 396.9±32.9 °C

The synthesis and biological evaluation of lactose-based sialylmimetics as inhibitors of rotaviral infection.

Bioorg. Med. Chem. 14 , 739-57, (2006)

Rotaviruses are the most significant cause of gastroenteritis in young children and are responsible for over 600,000 infant deaths annually. The rotaviral haemagglutinin protein (VP8*) of some strains has been implicated in early recognition and binding event...

Hemagglutinins from two influenza virus variants bind to sialic acid derivatives with millimolar dissociation constants: a 500-MHz proton nuclear magnetic resonance study.

Biochemistry 28 , 8388, (1989)

The equilibrium binding of influenza virus hemagglutinin to derivatives of its cell-surface ligand, sialic acid, was measured by nuclear magnetic resonance (NMR) spectroscopy. Binding was quantified by observing perturbations of sialic acid resonances in the ...

Sugar-binding sites of the HA1 subcomponent of Clostridium botulinum type C progenitor toxin.

J. Mol. Biol. 376 , 854-67, (2008)

Clostridium botulinum type C 16S progenitor toxin contains a hemagglutinin (HA) subcomponent, designated HA1, which appears to play an important role in the effective internalization of the toxin in gastrointestinal epithelial cells and in creating a broad sp...

Daman, M.E., and Dill, K.

Carbohydr. Res. 102 , 47, (1982)