Polyadenylic acid-Polyuridylic acid sodium salt
Polyadenylic acid-Polyuridylic acid sodium salt structure
|
Common Name | Polyadenylic acid-Polyuridylic acid sodium salt | ||
|---|---|---|---|---|
| CAS Number | 24936-38-7 | Molecular Weight | 671.40300 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H27N7O16P2 | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
|
RNA Binds to Tau Fibrils and Sustains Template-Assisted Growth.
Biochemistry 54 , 4731-40, (2015) Tau fibrils are the main proteinacious components of neurofibrillary lesions in Alzheimer disease. Although RNA molecules are sequestered into these lesions, their relationship to Tau fibrils is only poorly understood. Such understanding, however, is importan... |
|
|
Double domain swapping in bovine seminal RNase: formation of distinct N- and C-swapped tetramers and multimers with increasing biological activities.
PLoS ONE 7(10) , e46804, (2012) Bovine seminal (BS) RNase, the unique natively dimeric member of the RNase super-family, represents a special case not only for its additional biological actions but also for the singular features of 3D domain swapping. The native enzyme is indeed a mixture o... |
|
|
Immunoadjuvant effects of polyadenylic:polyuridylic acids through TLR3 and TLR7.
Int. Immunol. 20 , 1-9, (2008) Double-stranded RNA (dsRNA) is produced upon viral infection and can activate innate immunity. Polyinosinic:polycytidylic acids [poly(I:C)] is a synthetic mimetic of dsRNA and functions through an endosomal receptor, Toll-like receptor (TLR) 3 or cytosolic re... |
|
|
Binding of the anticancer alkaloid sanguinarine to double stranded RNAs: insights into the structural and energetics aspects.
Mol. Biosyst. 6(7) , 1265-76, (2010) Elucidation of the molecular aspects of small molecule-RNA complexation is of prime importance for rational RNA targeted drug design strategies. Towards this, the interaction of the cytotoxic plant alkaloid sanguinarine to three double stranded ribonucleic ac... |
|
|
[Energetics of hydration of nucleic acids with various nucleotide composition].
Biofizika 47(3) , 420-6, (2002) The energetics of hydration of natural DNA of different AT/GC content and model double-helical polyribonucleotides was studied. The results obtained by a new approach, which is based on calorimetric measurements of hydration-dehydration energy of nucleic acid... |
|
|
RNA-ligand interactions: affinity and specificity of aminoglycoside dimers and acridine conjugates to the HIV-1 Rev response element.
Biochemistry 42(39) , 11391-403, (2003) Semisynthetic aminoglycoside derivatives may provide a means to selectively target viral RNA sites, including the HIV-1 Rev response element (RRE). The design, synthesis, and evaluation of derivatives based upon neomycin B, kanamycin A, and tobramycin conjuga... |
|
|
A synthetic double-stranded RNA, poly I:C, induces a rapid apoptosis of human CD34(+) cells.
Exp. Hematol. 40(4) , 330-41, (2012) Toll-like receptor 3 (TLR3), retinoic acid-inducible gene I, and melanoma differentiation-associated antigen 5 (RIG-I/MDA-5) helicases are known to sense double-stranded RNA (dsRNA) virus and initiate antiviral responses, such as production of type-I interfer... |
|
|
The NIP7 protein is required for accurate pre-rRNA processing in human cells.
Nucleic Acids Res. 39(2) , 648-65, (2011) Eukaryotic ribosome biogenesis requires the function of a large number of trans-acting factors which interact transiently with the nascent pre-rRNA and dissociate as the ribosomal subunits proceed to maturation and export to the cytoplasm. Loss-of-function mu... |
|
|
Relaxation kinetics of the interaction between RNA and metal-intercalators: the Poly(A).Poly(U)/platinum-proflavine system.
Arch. Biochem. Biophys. 437(2) , 215-23, (2005) The interactions of Poly(A).Poly(U) with the cis-platinum derivative of proflavine [{PtCl(tmen)}(2){HNC(13)H(7)(NHCH(2)CH(2))(2)}](+) (PRPt) and proflavine (PR) are investigated by spectrophotometry, spectrofluorimetry and T-jump relaxation at I=0.2M, pH 7.0,... |
|
|
Probing the binding of two sugar bearing anticancer agents aristololactam-β-(D)-glucoside and daunomycin to double stranded RNA polynucleotides: a combined spectroscopic and calorimetric study.
Mol. Biosyst. 8(7) , 1958-69, (2012) The plant alkaloid aristololactam-β-d-glucoside and the anticancer chemotherapy drug daunomycin are two sugar bearing DNA binding antibiotics. The binding of these molecules to three double stranded ribonucleic acids, poly(A)·poly(U), poly(I)·poly(C) and poly... |