fluphenazine sulfoxide

fluphenazine sulfoxide Structure
fluphenazine sulfoxide structure
Common Name fluphenazine sulfoxide
CAS Number 1674-76-6 Molecular Weight 453.52100
Density 1.43g/cm3 Boiling Point 615.4ºC at 760mmHg
Molecular Formula C22H26F3N3O2S Melting Point 131-133ºC
MSDS N/A Flash Point 326ºC

Plasma levels of fluphenazine in patients receiving fluphenazine decanoate. Relationship to clinical response.

Br. J. Psychiatry 158 , 658-65, (1991)

The levels of fluphenazine and fluphenazine sulphoxide in schizophrenic patients who were randomly assigned to receive either 5 mg or 25 mg of fluphenazine decanoate every two weeks were monitored. Patients treated with 25 mg of fluphenazine decanoate require...

Impact of clinical pharmacokinetics on neuroleptic therapy in patients with schizophrenia.

J. Psychiatry Neurosci. 19(4) , 254-64, (1994)

This review covers some recent work on: 1. The effects of route of administration on the pharmacokinetics of fluphenazine and some of its metabolites; 2. The clinical pharmacokinetics of fluphenazine in acute patients medicated with oral fluphenazine; 3. The ...

The sulfoxidation of fluphenazine in schizophrenic patients maintained on fluphenazine decanoate.

Psychopharmacology 93(3) , 369-73, (1987)

Highly sensitive radioimmunoassays were applied to study the sulfoxidation of fluphenazine in 30 schizophrenic patients maintained on either 5 mg or 25 mg fluphenazine decanoate by intramuscular injection every 14 days over a period of 6 months. The presence ...

Radioimmunoassay for fluphenazine sulfoxide in human plasma.

J. Pharmacol. Methods 19(1) , 63-74, (1988)

Antisera to fluphenazine sulfoxide were raised in New Zealand white rabbits to an immunogen synthesized by covalent linkage of bovine serum albumin to 10-[[3-[4-(4-carboxybutyl)-1-piperazinyl] propyl]]-2-trifluoromethyl-10H-phenothiazine 5-sulfoxide. With use...