Neocarzinostatin
Neocarzinostatin structure
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Common Name | Neocarzinostatin | ||
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| CAS Number | 9014-02-2 | Molecular Weight | 661.65200 | |
| Density | 1.52g/cm3 | Boiling Point | 900.5ºC at 760 mmHg | |
| Molecular Formula | C35H35NO12 | Melting Point | N/A | |
| MSDS | USA | Flash Point | 498.4ºC | |
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Neocarzinostatin-chromophore: a potent inhibitor of casein kinase II in vitro. Tanoue, S., et al.
Antibiotics 51 , 95-98, (1998)
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The enediyne antibiotics.
J. Med. Chem. 39 , 2103-2117, (1996)
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Reinvestigation of the proteolytic activity of neocarzinostatin.
J. Bacteriol. 182 , 1812-1818, (2000) Neocarzinostatin (NCS) is the most studied member of a family of chromoproteins secreted by a range of actinomycetes species. It has been proposed that in addition to their antitumoral activity related to the bound chromophores, this group of related proteins... |
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DICER, DROSHA and DNA damage response RNAs are necessary for the secondary recruitment of DNA damage response factors.
J. Cell Sci. 129 , 1468-76, (2016) The DNA damage response (DDR) plays a central role in preserving genome integrity. Recently, we reported that the endoribonucleases DICER and DROSHA contribute to DDR activation by generating small non-coding RNAs, termed DNA damage response RNA (DDRNA), carr... |
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GABA maintains the proliferation of progenitors in the developing chick ciliary marginal zone and non-pigmented ciliary epithelium.
PLoS ONE 7 , e36874, (2012) GABA is more than the main inhibitory neurotransmitter found in the adult CNS. Several studies have shown that GABA regulates the proliferation of progenitor and stem cells. This work examined the effects of the GABA(A) receptor system on the proliferation of... |