SKF 77434 hydrobromide
SKF 77434 hydrobromide structure
|
Common Name | SKF 77434 hydrobromide | ||
|---|---|---|---|---|
| CAS Number | 300561-58-4 | Molecular Weight | 376.29 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H22BrNO2 | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
|
Dopamine-dependent desensitization of dopaminergic signaling in the developing mouse striatum.
J. Neurosci. 22(22) , 9841-9, (2002) The dynamics of dopamine receptor signaling efficacy were characterized in developing mice by measuring striatal c-Fos expression after dopaminergic agonist treatment at postnatal day 4 (P4) to P18. Control mice and mutant mice, in which dopamine production i... |
|
|
Age-related defects in spatial memory are correlated with defects in the late phase of hippocampal long-term potentiation in vitro and are attenuated by drugs that enhance the cAMP signaling pathway.
Proc. Natl. Acad. Sci. U. S. A. 96(9) , 5280-5, (1999) To study the physiological and molecular mechanisms of age-related memory loss, we assessed spatial memory in C57BL/B6 mice from different age cohorts and then measured in vitro the late phase of hippocampal long-term potentiation (L-LTP). Most young mice acq... |
|
|
Comparison of the D1-dopamine agonists SKF-38393 and A-68930 in neonatal 6-hydroxydopamine-lesioned rats: behavioral effects and induction of c-fos-like immunoreactivity.
J. Pharmacol. Exp. Ther. 262(2) , 855-65, (1992) Administration of the selective D1-dopamine receptor agonist 2,3,4,5-tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine (SKF-38393) to neonatal 6-hydroxydopamine-lesioned rats results in profound behavioral manifestations and induction of striatal c-fos-like ... |
|
|
Preventive medicine residents: a national survey.
Am. J. Prev. Med. 7(6) , 445-9, (1991) Little is known about those physicians who pursue graduate medical education in preventive medicine, including aerospace medicine, general preventive medicine and public health, and occupational medicine. We surveyed resident physicians about their academic b... |
|
|
Oxidant-induced cardiomyocyte injury: identification of the cytoprotective effect of a dopamine 1 receptor agonist using a cell-based high-throughput assay.
Int. J. Mol. Med. 20(5) , 749-61, (2007) Myocyte injury due to myocardial reperfusion injury plays a crucial role in the pathogenesis of acute myocardial infarction even after successful coronary revascularization. Identification of compounds that reduce reperfusion-associated myocyte death is impor... |
|
|
Drug discrimination in methamphetamine-trained monkeys: agonist and antagonist effects of dopaminergic drugs.
J. Pharmacol. Exp. Ther. 285 , 1163-1174, (1998) The involvement of D1 and D2 subtypes of dopamine receptors in behavioral effects of methamphetamine was studied in squirrel monkeys using a two-lever drug discrimination procedure. In monkeys that discriminated i.m. injections of 0.3 mg/kg methamphetamine fr... |
|
|
The relationship between reinforcing effects and in vitro effects of D1 agonists in monkeys.
J. Pharmacol. Exp. Ther. 283 , 29-38, (1997) The reinforcing effects of many psychomotor stimulants have been related to increased dopaminergic neurotransmission and stimulation of central nervous system (CNS) dopamine (DA) receptors. Consistent with this notion, some drugs that directly stimulate DA re... |
|
|
Evidence that the enhancement of dopamine function by repeated electroconvulsive shock requires concomitant activation of D1-like and D2-like dopamine receptors.
Psychopharmacology Berl. 133 , 77, (1997) In this study, the behavioural response to dopamine D1-like receptor agonists (SKF 38393, SKF 81297 and SKF 77434) and D2-like receptor agonists (quinpirole and RU 24213), administered alone and in combination to rats treated repeatedly with electroconvulsive... |