U-99194 maleate

U-99194 maleate Structure
U-99194 maleate structure
Common Name U-99194 maleate
CAS Number 234757-41-6 Molecular Weight 393.47400
Density N/A Boiling Point N/A
Molecular Formula C21H31NO6 Melting Point 146 - 147 °C
MSDS USA Flash Point N/A

Dopaminergic D2-like agonists produce yawning in the myelin mutant taiep and Sprague–Dawley rats

Pharmacol. Biochem. Behav. 102(1) , 118-23, (2012)

Systemic administration of D2-like dopaminergic-receptor agonists increases yawning behavior. However, only a few studies have been done in animals with pathological conditions. The taiep rat is a myelin mutant with an initial hypomyelination followed by prog...

Presynaptic dopaminergic agonists increased gripping-generated immobility episodes in the myelin-mutant taiep rat.

Neurosci. Lett. 483(3) , 189-92, (2010)

The taiep rat is a myelin mutant whose immobility episodes (IEs) can be caused by gripping them by the tail. Electroencephalographic recordings during IEs show a rapid-eye movement sleep-like pattern, similar to narcolepsy-cataplexy in canines. Systemic admin...

The dopamine D3-receptor: a postsynaptic receptor inhibitory on rat locomotor activity.

J. Neural Transm. Gen. Sect. 94 , 11-19, (1993)

We report on the pharmacological effects of the 20 fold D3 vs. D2 dopamine receptor preferring compound U99194A. It is shown that U99194A increases rat locomotor activity at doses that do not increase release or utilisation of dopamine in the striatum or the ...

Effects on locomotor activity after local application of D3 preferring compounds in discrete areas of the rat brain.

J. Neural Transm. Gen. Sect. 102 , 209-220, (1995)

Compounds showing an in vitro binding preference for the dopamine D3 vs. D2 receptors were tested for effects on locomotor activity after local application in the nucleus accumbens (N Acc) and the ventral tegmental area (VTA) of the rat brain. R-(+)-7-OH-DPAT...