DL-1,3-DIHYDROXY-2-AMINO-OCTADECANE

DL-1,3-DIHYDROXY-2-AMINO-OCTADECANE Structure
DL-1,3-DIHYDROXY-2-AMINO-OCTADECANE structure
Common Name DL-1,3-DIHYDROXY-2-AMINO-OCTADECANE
CAS Number 13552-09-5 Molecular Weight 301.50800
Density 0.927g/cm3 Boiling Point 446.2ºC at 760mmHg
Molecular Formula C18H39NO2 Melting Point N/A
MSDS Chinese USA Flash Point 223.7ºC

Picomole scale stereochemical analysis of sphingosines and dihydrosphingosines.

Bioorg. Med. Chem. 4 , 1035, (1996)

We have developed a simple picomole (low nanogram) scale HPLC scheme which can separate all eight isomers of sphingosine and dihydrosphingosine thus leading to the identification of their relative and absolute configurations. The amino group of the sample is ...

Sphingosine blocks human polymorphonuclear leukocyte phagocytosis through inhibition of mitogen-activated protein kinase activation.

Blood 93 , 686-693, (1999)

In the present study, we investigated the mechanism by which sphingosine and its analogues, dihydrosphingosine and phytosphingosine, inhibit polymorphonuclear leukocyte (PMN) phagocytosis of IgG-opsonized erythrocytes (EIgG) and inhibit ERK1 and ERK2 phosphor...