![]() BENOXATHIAN HCL structure
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Common Name | BENOXATHIAN HCL | ||
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CAS Number | 92642-97-2 | Molecular Weight | 397.91600 | |
Density | N/A | Boiling Point | 500.7ºC at 760 mmHg | |
Molecular Formula | C19H24ClNO4S | Melting Point | N/A | |
MSDS | Chinese USA | Flash Point | 256.6ºC |
Liquid chromatography-quadrupole time-of-flight mass spectrometry for screening in vitro drug metabolites in humans: investigation on seven phenethylamine-based designer drugs.
J. Pharm. Biomed. Anal. 114 , 355-75, (2015) Phenethylamine-based designer drugs are prevalent within the new psychoactive substance market. Characterisation of their metabolites is important in order to identify suitable biomarkers which can be used for better monitoring their consumption. Careful desi... |
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α1-Adrenergic drugs modulate differentiation and cell death of human erythroleukemia cells through non adrenergic mechanism.
Exp. Cell Res. 317(16) , 2239-51, (2011) Preliminary data showed that α1-adrenergic antagonists induce apoptosis and a switch towards megakaryocytic differentiation in human erythroleukemia cells. To test the hypothesis whether survival and differentiation of erythroleukemia cells are under control ... |
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Activated endothelial cells limit inflammatory response, but increase chemoattractant potential and bacterial clearance by human monocytes.
Cell Biol. Int. 39 , 721-32, (2015) Inflammation is the normal immune response of vascularized tissues to damage and bacterial products, for which leukocyte transendothelial migration (TEM) is critical. The effects of cell-to-cell contact seen in both leukocyte and endothelial cells include cyt... |
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The dose dependent in vitro responses of MCF-7 and MDA-MB-231 cell lines to extracts of Vatica diospyroides symington type SS fruit include effects on mode of cell death.
Pharmacogn. Mag. 11 , S148-55, (2015) Vatica diospyroides type LS is a known source of valuable compounds for cancer treatment, however, in contrast little is known about therapeutic efficacy of type SS.This study focused on in vitro cytotoxicity of these fruit extracts, and the cell death mode t... |
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The cellular origin and malignant transformation of Waldenström macroglobulinemia.
Blood 125 , 2370-80, (2015) Although information about the molecular pathogenesis of Waldenström macroglobulinemia (WM) has significantly advanced, the precise cell of origin and the mechanisms behind WM transformation from immunoglobulin-M (IgM) monoclonal gammopathy of undetermined si... |
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Detection of MYD88 L265P mutation by real-time allele-specific oligonucleotide polymerase chain reaction.
Appl. Immunohistochem. Mol. Morphol. 22(10) , 768-73, (2014) MYD88 L265P mutation has been reported in ∼90% of Waldenström's Macroglobulinemia (WM) patients and immunoglobulin M (IgM) monoclonal gammopathies of uncertain significance (MGUS), as well as in some cases of lymphoma and chronic lymphocytic leukemia. The pre... |
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Aggressive mature natural killer cell neoplasms: report on a series of 12 European patients with emphasis on flow cytometry based immunophenotype and DNA content of neoplastic natural killer cells.
Leuk. Lymphoma 56(1) , 103-12, (2015) We report 12 cases of aggressive natural killer (NK) cell neoplasms diagnosed in Portugal, with emphasis on flow cytometry. Ten patients had extranodal NK/T cell lymphoma, nasal type and two had aggressive NK cell leukemia, and seven were men and five were wo... |
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Investigation of the subtypes of alpha1-adrenoceptor mediating contractions of rat vas deferens.
Br. J. Pharmacol. 128 , 1323-1331, (1999) 1 The subtypes of alpha1-adrenoceptor mediating contractions of rat vas deferens to endogenous and exogenous noradrenaline and to the exogenous agonists methoxamine, phenylephrine and A61603 have been examined. 2 The effects of antagonists on the shape of con... |
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Medial prefrontal cortical alpha1 adrenoreceptor modulation of the nucleus accumbens dopamine response to stress in Long-Evans rats.
Psychopharmacology 191(3) , 835-42, (2007) The medial prefrontal cortex (PFC) receives stress-sensitive dopamine (DA) and noradrenergic (NE) projections from the ventral tegmental area and locus coeruleus, respectively, and evidence from various sources point to a complex functional interaction betwee... |
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Pharmacological characterization of alpha1- and beta-adrenergic synergism of 5'DII activity in rat brown adipocytes.
Arch. Physiol. Biochem. 112(1) , 23-30, (2006) The role of adrenoceptor subtypes was studied in rat brown adipose tissue (BAT). The type II 5'-deiodinase (5'DII) was activated in response to simultaneous stimulation by beta3- and alpha1-adrenergic agonists, BRL 37344 or CGP 12177, and cirazoline, in brown... |