KC7F2

KC7F2 Structure
KC7F2 structure
Common Name KC7F2
CAS Number 927822-86-4 Molecular Weight 570.381
Density 1.6±0.1 g/cm3 Boiling Point 708.8±70.0 °C at 760 mmHg
Molecular Formula C16H16Cl4N2O4S4 Melting Point N/A
MSDS Chinese USA Flash Point 382.5±35.7 °C

Hypoxia-inducible TAp73 supports tumorigenesis by regulating the angiogenic transcriptome.

Nat. Cell Biol. 17(4) , 511-23, (2015)

The functional significance of the overexpression of unmutated TAp73, a homologue of the tumour suppressor p53, in multiple human cancers is unclear, but raises the possibility of unidentified roles in promoting tumorigenesis. We show here that TAp73 is stabi...

Oct-3/4 promotes tumor angiogenesis through VEGF production in glioblastoma.

Brain Tumor Pathol. 32(1) , 31-40, (2015)

Accumulating evidence shows that the expression level of Oct-3/4, a self-renewal regulator in stem cells, is positively correlated with the progression of various solid tumors. However, little is known regarding the influence of Oct-3/4 in the tumor angiogene...

Lenticular cytoprotection. Part 1: the role of hypoxia inducible factors-1α and -2α and vascular endothelial growth factor in lens epithelial cell survival in hypoxia.

Mol. Vis. 19 , 1-15, (2013)

The prosurvival signaling cascades that mediate the unique ability of human lens epithelial cells to survive in their naturally hypoxic environment are not well defined. Hypoxia induces the synthesis of the hypoxia inducible factor HIF-1α that in turn, plays ...