Ascochlorin

Ascochlorin Structure
Ascochlorin structure
Common Name Ascochlorin
CAS Number 26166-39-2 Molecular Weight 404.92700
Density 1.199g/cm3 Boiling Point 556.9ºC at 760mmHg
Molecular Formula C23H29ClO4 Melting Point N/A
MSDS Chinese USA Flash Point 290.6ºC

Silibinin suppresses PMA-induced MMP-9 expression by blocking the AP-1 activation via MAPK signaling pathways in MCF-7 human breast carcinoma cells.

Biochem. Biophys. Res. Commun. 354(1) , 165-71, (2007)

Matrix metalloproteinase-9 (MMP-9) plays an important role in the invasion and metastasis of cancer cells. In this study, we examined the inhibitory effect of silibinin, a flavonoid antioxidant from milk thistle (Silybum marianum L.) on PMA-induced MMP-9 expr...