Eicosapentaenoic Acid
Eicosapentaenoic Acid structure
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Common Name | Eicosapentaenoic Acid | ||
|---|---|---|---|---|
| CAS Number | 10417-94-4 | Molecular Weight | 302.451 | |
| Density | 0.9±0.1 g/cm3 | Boiling Point | 439.3±24.0 °C at 760 mmHg | |
| Molecular Formula | C20H30O2 | Melting Point | -54--53ºC(lit.) | |
| MSDS | USA | Flash Point | 336.0±18.0 °C | |
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Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Chem. Res. Toxicol. 23 , 171-83, (2010) Drug-induced liver injury is one of the main causes of drug attrition. The ability to predict the liver effects of drug candidates from their chemical structures is critical to help guide experimental drug discovery projects toward safer medicines. In this st... |
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HMDB: a knowledgebase for the human metabolome.
Nucleic Acids Res. 37(Database issue) , D603-10, (2009) The Human Metabolome Database (HMDB, http://www.hmdb.ca) is a richly annotated resource that is designed to address the broad needs of biochemists, clinical chemists, physicians, medical geneticists, nutritionists and members of the metabolomics community. Si... |
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The human serum metabolome.
PLoS ONE 6(2) , e16957, (2011) Continuing improvements in analytical technology along with an increased interest in performing comprehensive, quantitative metabolic profiling, is leading to increased interest pressures within the metabolomics community to develop centralized metabolite ref... |
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Lipidomics reveals a remarkable diversity of lipids in human plasma.
J. Lipid Res. 51(11) , 3299-305, (2010) The focus of the present study was to define the human plasma lipidome and to establish novel analytical methodologies to quantify the large spectrum of plasma lipids. Partial lipid analysis is now a regular part of every patient's blood test and physicians r... |
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Interference by naturally occurring fatty acids in a noncellular enzyme-based aromatase bioassay.
J. Nat. Prod. 69 , 700-3, (2006) Natural product drug discovery efforts frequently utilize noncellular screening assays. Fatty acids are commonly found in natural product extracts, and some have been shown to interfere with noncellular assays. Several pure fatty acids were tested using a non... |
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Inhibitory effect of novel 5-O-acyl juglones on mammalian DNA polymerase activity, cancer cell growth and inflammatory response.
Bioorg. Med. Chem. 19 , 5803-5812, (2011) We previously found that vitamin K(3) (menadione, 2-methyl-1,4-naphthoquinone) inhibits the activity of human mitochondrial DNA polymerase γ (pol γ). In this study, we focused on juglone (5-hydroxy-1,4-naphthoquinone), which is a 1,4-naphthoquinone derivative... |
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Fasting serum free fatty acid composition, waist/hip ratio and insulin activity in essential hypertensive patients.
Hypertens. Res. 31(4) , 623-32, (2008) Abnormal fatty acid metabolism may play an important role in the pathogenesis of essential hypertension (EH). We compared fasting serum free fatty acid (FFA) composition between EH patients and nonhypertensive (NH) subjects, and examined the relationships bet... |
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Analysis of biogenic amines in plasma of hypertensive patients and a control group.
Neurochem. Res. 18(11) , 1179-82, (1993) Procedures were developed for the determination of 17 circulating amines using gas chromatography-negative ion chemical ionisation mass spectrometry. The amines were quantified against their appropriate deuterated isotopomers. The mean concentrations and rang... |
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Urinary tetrahydroaldosterone as a screening method for primary aldosteronism: a comparative study.
Am. J. Hypertens. 16(7) , 522-30, (2003) The major aldosterone metabolite 3 alpha,5 beta tetrahydroaldosterone reflects up to 45% of the aldosterone secretion. Its 24-h urinary excretion is likely to provide an accurate index of the daily aldosterone production and to be an indicator for primary ald... |
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Altered release of cytochrome p450 metabolites of arachidonic acid in renovascular disease.
Hypertension 51(5) , 1379-85, (2008) The aim of the present cross-sectional study was to investigate whether activation of the renin-angiotensin system in renovascular disease affects the cytochrome P450 omega/omega-1 hydroxylase (20-hydroxyeicosatetraenoic acid [20-HETE]) and epoxygenase (epoxy... |