2-Methacryloyloxyethyl phosphorylcholine

2-Methacryloyloxyethyl phosphorylcholine Structure
2-Methacryloyloxyethyl phosphorylcholine structure
Common Name 2-Methacryloyloxyethyl phosphorylcholine
CAS Number 67881-98-5 Molecular Weight 295.27
Density N/A Boiling Point N/A
Molecular Formula C11H22NO6P Melting Point 143-148°C
MSDS Chinese USA Flash Point N/A

Zwitterionic red fluorescent polymeric nanoparticles for cell imaging.

Macromol. Biosci. 14(10) , 1361-7, (2014)

Phospholipid monomer and aggregation-induced emission (AIE) dye-based dimers are incorporated via reversible addition-fragmentation transfer polymerization to afford cross-linked zwitterionic fluorescent copolymers. Such copolymers are prone to self-assembly ...

Sorafenib resistance and JNK signaling in carcinoma during extracellular matrix stiffening.

Biomaterials 35(22) , 5749-59, (2014)

Tumor progression is coincident with mechanochemical changes in the extracellular matrix (ECM). We hypothesized that tumor stroma stiffening, alongside a shift in the ECM composition from a basement membrane-like microenvironment toward a dense network of col...

Oncogenic Ras/ERK signaling activates CDCP1 to promote tumor invasion and metastasis.

Mol. Cancer Res. 12(10) , 1449-59, (2014)

Involvement of Ras in cancer initiation is known, but recent evidence indicates a role in cancer progression, including metastasis and invasion; however, the mechanism is still unknown. In this study, it was determined that human lung cancer cells with Ras mu...

Real time visualization and characterization of platelet deposition under flow onto clinically relevant opaque surfaces.

J. Biomed. Mater. Res. A 103(4) , 1303-11, (2015)

Although the thrombogenic nature of the surfaces of cardiovascular devices is an important aspect of blood biocompatibility, few studies have examined platelet deposition onto opaque materials used for these devices in real time. This is particularly true for...

Long-term hip simulator testing of the artificial hip joint bearing surface grafted with biocompatible phospholipid polymer.

J. Orthop. Res. 32(3) , 369-76, (2014)

To prevent periprosthetic osteolysis and subsequent aseptic loosening of artificial hip joints, we recently developed a novel acetabular highly cross-linked polyethylene (CLPE) liner with graft polymerization of 2-methacryloyloxyethyl phosphorylcholine (MPC) ...

Preparation of non-thrombogenic materials using 2-methacryloyloxyethyl phosphorylcholine.

Biomaterials 24(13) , 2431-5, (2003)

This review addresses the non-thrombogenic characteristics of copolymers based on 2-methacryloyloxyethyl phosphorylcholine (MPC), originally developed by Nakabayashi and colleagues. The hypothesis underlying these developments was that such materials would ad...

Copolymers of 2-methacryloyloxyethyl phosphorylcholine (MPC) as biomaterials.

Biomed Mater Eng 14(4) , 345-54, (2004)

Copolymers of 2-methacryloyloxyethyl phosphorylcholine (MPC) showed good hemocompatibility as hypothesized. The hypothesis was surfaces having phosphorylcholine groups by polymerization of MPC could accumulate phospholipids from blood stream and show good blo...