Citicoline sodium salt
Citicoline sodium salt structure
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Common Name | Citicoline sodium salt | ||
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| CAS Number | 33818-15-4 | Molecular Weight | 511.31 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C14H26N4NaO11P2 | Melting Point | 259-268°C (dec.) | |
| MSDS | USA | Flash Point | N/A | |
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Gemcitabine diphosphate choline is a major metabolite linked to the Kennedy pathway in pancreatic cancer models in vivo.
Br. J. Cancer 111(2) , 318-25, (2014) The modest benefits of gemcitabine (dFdC) therapy in patients with pancreatic ductal adenocarcinoma (PDAC) are well documented, with drug delivery and metabolic lability cited as important contributing factors. We have used a mouse model of PDAC: KRAS(G12D); ... |
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A randomized dose-response trial of citicoline in acute ischemic stroke patients. Citicoline Stroke Study Group.
Neurology 49 , 671-678, (1997) Citicoline (CDP-choline) is a key intermediary in the biosynthesis of phosphatidylcholine, an important component of the neural cell membrane. It has been shown to produce beneficial effects in both animal models and non-US clinical stroke trials. This study ... |
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Synergistic effects of citicoline and MK-801 in temporary experimental focal ischemia in rats.
Stroke 28 , 1060-1065, (1997) Citicoline, a naturally occurring precursor of phosphatidylcholine, is neuroprotective and is currently being assessed in clinical trials. To evaluate potential synergistic neuroprotective effects of prolonged citicoline treatment and early N-methyl-D-asparta... |
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The effects of prolonged treatment with citicoline in temporary experimental focal ischemia.
J. Neurol. Sci. 38 , 21-25, (1996) Potential therapeutic effects of cytidine 5-diphosphocholine (citicoline), a key intermediary in the biosynthesis of the membrane phospholipid, phosphatidylcholine, are presumably related to enhanced phospholipid synthesis in the ischemic brain. We evaluated ... |