Adenosine-5'-diphosphate disodium salt

Adenosine-5'-diphosphate disodium salt Structure
Adenosine-5'-diphosphate disodium salt structure
Common Name Adenosine-5'-diphosphate disodium salt
CAS Number 16178-48-6 Molecular Weight 471.165
Density N/A Boiling Point 877.7ºC at 760 mmHg
Molecular Formula C10H13N5Na2O10P2 Melting Point N/A
MSDS USA Flash Point 484.6ºC

A novel surface-confined glucaminium-based ionic liquid stationary phase for hydrophilic interaction/anion-exchange mixed-mode chromatography.

J. Chromatogr. A. 1360 , 240-7, (2014)

Glucaminium-based ionic liquids are a new class of recently developed ionic liquids and prepared by functionalizing the amine group of N-methyl-d-glucamine, which renders them good hydrophilicity due to the presence of the glucose structure and charged quater...

Adenosine derived from ADP can contribute to inhibition of platelet aggregation in the presence of a P2Y12 antagonist.

Arterioscler. Thromb. Vasc. Biol. 31 , 416-422, (2011)

To investigate whether adenosine diphosphate (ADP)-derived adenosine might inhibit platelet aggregation, especially in the presence of a P2Y₁₂ antagonist, where the effects of ADP at the P2Y₁₂ receptor would be prevented.Platelet aggregation was measured in r...

Extracellular Ca(2+) modulates ADP-evoked aggregation through altered agonist degradation: implications for conditions used to study P2Y receptor activation.

Br. J. Haematol. 153 , 83-91, (2011)

ADP is considered a weak platelet agonist due to the limited aggregation responses it induces in vitro at physiological concentrations of extracellular Ca(2+) [(Ca(2+) )(o) ]. Lowering [Ca(2+) ](o) paradoxically enhances ADP-evoked aggregation, an effect that...

P2Y receptors in health and disease.

Adv. Pharmacol. 61 , 417-439, (2011)

The purine- and pyrimidine-sensitive P2Y receptors belong to the large group of G-protein-coupled receptors that are the target of approximately one-third of the pharmaceutical drugs used in the clinic today. It is therefore not unexpected that the P2Y recept...

P2 receptors and platelet function.

Purinergic Signal. 7(3) , 293-303, (2011)

Following vessel wall injury, platelets adhere to the exposed subendothelium, become activated and release mediators such as TXA(2) and nucleotides stored at very high concentration in the so-called dense granules. Released nucleotides and other soluble agent...