5-Fluorotryptamine hydrochloride
5-Fluorotryptamine hydrochloride structure
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Common Name | 5-Fluorotryptamine hydrochloride | ||
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| CAS Number | 2711-58-2 | Molecular Weight | 214.667 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 346.0±27.0 °C at 760 mmHg | |
| Molecular Formula | C10H12ClFN2 | Melting Point | 277-283 | |
| MSDS | Chinese USA | Flash Point | 163.0±23.7 °C | |
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5-Fluorotryptamine is a partial agonist at 5-HT3 receptors, and reveals that size and electronegativity at the 5 position of tryptamine are critical for efficient receptor function.
Eur. J. Pharmacol. 580(3) , 291-7, (2008) Antagonists, but not agonists, of the 5-HT3 receptor are useful therapeutic agents, and it is possible that partial agonists may also be potentially useful in the clinic. Here we show that 5-fluorotryptamine (5-FT) is a partial agonist at both 5-HT3A and 5-HT... |
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Quantitative determination of melatonin in human plasma and cerebrospinal fluid with high-performance liquid chromatography and fluorescence detection.
Biomed. Chromatogr. 14(5) , 306-10, (2000) A validated new and precise reversed-phase high-performance liquid chromatographic method for the determination of melatonin in human plasma and cerebrospinal fluid, with 5-fluorotryptamine as internal standard, is described. Liquid-liquid extraction with dic... |
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Thrombin: active-site topography.
Ann. N. Y. Acad. Sci. 485 , 80-95, (1986)
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Pharmacological profile of the 5-hydroxytryptamine receptor of Fasciola hepatica body wall muscle.
Parasitology 106 ( Pt 1) , 67-73, (1993) 5-HT is a candidate for the excitatory transmitter at the neuromuscular junction in trematodes including Fasciola hepatica. This study has determined the response of a muscle strip preparation from Fasciola hepatica to 5-HT and a range of agonists that distin... |
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Binding of 5-fluorotryptamine to polynucleotides as a model for protein-nucleic acid interactions: fluorine-19 nuclear magnetic resonance, absorption, and fluorescence studies.
Biochemistry 21(4) , 615-20, (1982) Fluorine-19 nuclear magnetic resonance (19F NMR), optical absorption, and fluorescence spectroscopy have been used to study the interaction of 5-fluorotryptamine (5FTA) with polynucleotides as a model for protein--nucleic acid interactions. In the presence of... |