DL-Thyronine

DL-Thyronine Structure
DL-Thyronine structure
Common Name DL-Thyronine
CAS Number 1034-10-2 Molecular Weight 273.28
Density 1.3±0.1 g/cm3 Boiling Point 477.7±45.0 °C at 760 mmHg
Molecular Formula C15H15NO4 Melting Point N/A
MSDS N/A Flash Point 242.7±28.7 °C

Loss of Snail2 favors skin tumor progression by promoting the recruitment of myeloid progenitors.

Carcinogenesis 36 , 585-97, (2015)

Snail2 is a zinc finger transcription factor involved in driving epithelial to mesenchymal transitions. Snail2 null mice are viable, but display defects in melanogenesis, gametogenesis and hematopoiesis, and are markedly radiosensitive. Here, using mouse gene...

Differential Gene Regulation in Fibroblasts in Co-culture with Keratinocytes and Head and Neck SCC Cells.

Anticancer Res. 35 , 3253-65, (2015)

While carcinoma-associated fibroblasts (CAFs) support tumorigenesis, normal tissue fibroblasts suppress tumor progression. Mechanisms behind conversion of fibroblasts into a CAF phenotype are largely unrevealed.Transwell co-cultures with fibroblasts in collag...

Rubi Fructus (Rubus coreanus) activates the expression of thermogenic genes in vivo and in vitro.

Int. J. Obes. 39(3) , 456-64, (2015)

To investigate the anti-obesity effect of Rubi Fructus (RF) extract using brown adipose tissue (BAT) and primary brown preadipocytes in vivo and in vitro.Male C57BL/6 J mice (n=5 per group) were fed a high-fat diet (HFD) for 10 weeks with or without RF. Brown...

Gleaning unexpected fruits from hard-won synthetases: probing principles of permissivity in non-canonical amino acid-tRNA synthetases.

ChemBioChem. 15(12) , 1810-9, (2014)

The site-specific incorporation of non-canonical amino acids (ncAAs) into proteins is an important tool for understanding biological function. Traditionally, each new ncAA targeted for incorporation requires a resource-consuming process of generating new ncAA...

Reconstitution of kidney side population cells after ischemia-reperfusion injury by self-proliferation and bone marrow-derived cell homing.

Evid. Based. Complement. Alternat. Med. 2013 , 370961, (2013)

The aim of this study was to examine the contribution of side population (SP) cells from kidney and bone marrow for reconstitution of kidney SP pools after ischemia-reperfusion injury (IRI). The SP and non-SP cells in kidneys following IRI were isolated and s...

Protein tyrosine phosphatase receptor type z negatively regulates oligodendrocyte differentiation and myelination.

PLoS ONE 7 , e48797, (2012)

Fyn tyrosine kinase-mediated down-regulation of Rho activity through activation of p190RhoGAP is crucial for oligodendrocyte differentiation and myelination. Therefore, the loss of function of its counterpart protein tyrosine phosphatase (PTP) may enhance mye...

The variable region of iodothyronine deiodinases directs their catalytic properties and subcellular localization.

Mol. Cell. Endocrinol. 402 , 107-12, (2015)

The stereospecific removal of iodine from thyroid hormones is an essential first step for T3 action and is catalyzed by three different deiodinases: D2 and D3 remove iodine only from the outer or inner ring, respectively, whereas D1 catalyzes both pathways. W...

Clinical and genetic characteristics of a large monocentric series of patients affected by thyroid hormone (Th) resistance and suggestions for differential diagnosis in patients without mutation of Th receptor β.

Clin. Endocrinol. (Oxf.) 81(6) , 921-8, (2014)

The syndrome of resistance to thyroid hormone (RTH) is caused by a mutation of TH receptor β (TRβ) in 80% of cases. Patients without mutation (non-TR-RTH) may have a biochemical pattern that is difficult to differentiate from that of pituitary TSH-secreting a...