α-Aminoadipic acid

α-Aminoadipic acid Structure
α-Aminoadipic acid structure
Common Name α-Aminoadipic acid
CAS Number 7620-28-2 Molecular Weight 161.156
Density 1.3±0.1 g/cm3 Boiling Point 364.0±32.0 °C at 760 mmHg
Molecular Formula C6H11NO4 Melting Point 208-210 °C(lit.)
MSDS Chinese USA Flash Point 173.9±25.1 °C

Inhibition of the glutamate transporter and glial enzymes in rat striatum by the gliotoxin, alpha aminoadipate.

Br. J. Pharmacol. 113 , 536-540, (1994)

1. The effect of the gliotoxic analogue of glutamate, alpha aminoadipate, on the high affinity transport of D-[3H]-aspartate into a crude striatal P2 preparation, and on the activity of two enzymes of which glutamate is the substrate has been examined. 2. The...

The glio-toxic mechanism of alpha-aminoadipic acid on cultured astrocytes.

J. Neurocytol. 27 , 109, (1998)

The mechanism of action of the glutamate analogue alpha-aminoadipic (AAA) acid was investigated in terms of its toxicity to cultured astrocytes. AAA was more toxic to type 1 astrocytes than type 2 astrocytes. Also the higher toxicity of the L-isomer as compar...

The effects of D-alpha-aminoadipic acid on long-term potentiation in the hippocampus of the rat in vitro.

J. Neurosci. Res. 24 , 139-150, (1996)

Many studies on long-term potentiation (LTP) in hippocampal region CA1 focus on receptor-mediated events that are often presumed to be linked to postsynaptic processes. Whereas it is now well-known that LTP consists of multiple components involving increases ...