4-[4-Chloro-3-(trifluoromethyl)phenyl]-4-piperidinol

4-[4-Chloro-3-(trifluoromethyl)phenyl]-4-piperidinol Structure
4-[4-Chloro-3-(trifluoromethyl)phenyl]-4-piperidinol structure
Common Name 4-[4-Chloro-3-(trifluoromethyl)phenyl]-4-piperidinol
CAS Number 21928-50-7 Molecular Weight 279.68600
Density 1.347 g/cm3 Boiling Point 333.3ºC at 760 mmHg
Molecular Formula C12H13ClF3NO Melting Point 138-141 °C(lit.)
MSDS Chinese USA Flash Point 155.4ºC

Discovery, synthesis, and biological evaluation of piperidinol analogs with anti-tuberculosis activity.

Bioorg. Med. Chem. 17 , 3588-3594, (2009)

Direct anti-tuberculosis screening of commercially available compound libraries identified a novel piperidinol with interesting anti-tuberculosis activity and drug like characteristics. To generate a structure activity relationship about this hit a 22 member ...

Rhodium catalyzed hydroformylation of 1, 1-bis (p-fluorophenyl) allyl or propargyl alcohol: a key step in the synthesis of Fluspirilen and Penfluridol. Botteghi C, et al.

Tetrahedron 57(8) , 1631-1637, (2001)