XTT sodium

XTT sodium Structure
XTT sodium structure
Common Name XTT sodium
CAS Number 111072-31-2 Molecular Weight 715.53400
Density N/A Boiling Point N/A
Molecular Formula C22H16N7NaO13S2 Melting Point 41678ºC
MSDS Chinese USA Flash Point N/A

Rapid Bioassay-Guided Isolation of Antibacterial Clerodane Type Diterpenoid from Dodonaea viscosa (L.) Jaeq.

Int. J. Mol. Sci. 16 , 20290-307, (2015)

Plant extracts are complex matrices and, although crude extracts are widely in use, purified compounds are pivotal in drug discovery. This study describes the application of automated preparative-HPLC combined with a rapid off-line bacterial bioassay, using r...

In vitro modulation of probiotic bacteria on the biofilm of Candida glabrata.

Anaerobe 34 , 132-8, (2015)

A conspicuous new concept of pathogens living as the microbial societies in the human host rather than free planktonic cells has raised considerable concerns among scientists and clinicians. Fungal biofilms are communities of cells that possess distinct chara...

Interactions of cyclin-dependent kinase inhibitors AT-7519, flavopiridol and SNS-032 with ABCB1, ABCG2 and ABCC1 transporters and their potential to overcome multidrug resistance in vitro.

Cancer Chemother. Pharmacol. 76 , 105-16, (2015)

ATP-binding cassette (ABC) transporters play an important role in multidrug resistance (MDR) toward anticancer drugs. Here, we evaluated interactions of cyclin-dependent kinase inhibitors (CDKi) AT-7519, flavopiridol and SNS-032 with the following ABC transpo...

Improvement of XTT assay performance for studies involving Candida albicans biofilms.

Braz. Dent. J. 19 , 264-9, (2008)

2, 3-bis (2-methoxy-4-nitro-5-sulfophenyl)-5-[(phenylamino) carbonyl]-2H-tetrazolium hydroxide (XTT) reduction assay has been used to study Candida biofilm formation. However, considering that the XTT reduction assay is dependent on cell activity, its use for...

Improved short- and long-term XTT-based colorimetric cellular cytotoxicity assay for melanoma and other tumor cells.

J. Immunol. Methods 147(2) , 153-65, (1992)

A tetrazolium compound, XTT, bioreducible to a water-soluble formazan was used to develop a simplified cellular cytotoxicity assay. Most (13/15 melanoma and 2/3 colon carcinoma cell lines tested metabolized XTT greater than 50 times more efficiently than the ...

An improved colorimetric assay for cell proliferation and viability utilizing the tetrazolium salt XTT.

J. Immunol. Methods 142 , 257-265, (1991)

A new tetrazolium salt XTT, sodium 3'-[1-[(phenylamino)-carbonyl]-3,4-tetrazolium]-bis(4-methoxy-6- nitro)benzene-sulfonic acid hydrate, was evaluated for use in a colorimetric assay for cell viability and proliferation by normal activated T cells and several...

Evaluation of a soluble tetrazolium/formazan assay for cell growth and drug sensitivity in culture using human and other tumor cell lines.

Cancer Res. 48 , 4827, (1988)

We have previously described the application of an automated microculture tetrazolium assay (MTA) involving dimethyl sulfoxide solubilization of cellular-generated 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT)-formazan to the in vitro ass...

Parsons, J.L., et al.

J. Heterocycl. Chem. 25 , 911, (1988)