2-amino-4,5-dimethylphenylamine

2-amino-4,5-dimethylphenylamine Structure
2-amino-4,5-dimethylphenylamine structure
Common Name 2-amino-4,5-dimethylphenylamine
CAS Number 3171-45-7 Molecular Weight 136.194
Density 1.1±0.1 g/cm3 Boiling Point 279.6±35.0 °C at 760 mmHg
Molecular Formula C8H12N2 Melting Point 127-129 °C(lit.)
MSDS USA Flash Point 144.9±25.4 °C

The acute phase protein ceruloplasmin as a non-invasive marker of pseudopregnancy, pregnancy, and pregnancy loss in the giant panda.

PLoS ONE 6(7) , e21159, (2011)

After ovulation, non-pregnant female giant pandas experience pseudopregnancy. During pseudopregnancy, non-pregnant females exhibit physiological and behavioral changes similar to pregnancy. Monitoring hormonal patterns that are usually different in pregnant m...

Synthesis of new derivatives of 4-acylquinoxalin-2-ones with potential pharmacological activity.

Acta Pol. Pharm. 51 , 231, (1994)

Some of new derivatives of 4-acylquinoxalin-2-one obtained in the reaction of N,N'-bis(chloroacetyl)-4,5-dimethyl-o-phenylenediamine with primary amines are described. Compounds were tested for their anti-HIV activity and as ligands for 99mTc.

Ruthenium(II) arene anticancer complexes with redox-active diamine ligands.

Inorg. Chem. 48(19) , 9444-53, (2009)

The synthesis and characterization of ruthenium(II) arene complexes of the general formula [(eta(6)-arene)Ru(XY)Z](+), where arene = p-cymene (p-cym), hexamethylbenzene (hmb), or biphenyl (bip), XY = o-phenylenediamine (o-pda), o-benzoquinonediimine (o-bqdi),...

Development and validation of a liquid chromatographic method for the determination of ascorbic acid, dehydroascorbic acid and acetaminophen in pharmaceuticals.

J. Pharm. Biomed. Anal. 48(2) , 331-9, (2008)

A reversed-phase ion pair liquid chromatographic method (RP-LC) for the determination of dehydroascorbic acid (DHA) and ascorbic acid (AA) and also acetaminophen, which is combined in pharmaceuticals, is proposed and validated. AA and acetaminophen were analy...

Aspects of the release of superoxide by leukocytes, and a means by which this is switched off.

Environ. Health Perspect. 102 Suppl 10 , 43-4, (1994)

Although great progress has been made in understanding the respiratory burst of leukocytes that produce superoxide (O2-), it is possible that a component or components, might have been overlooked. Furthermore, O2- production and its sequels, though cardinal i...

Methoxatin (PQQ) in guinea-pig neutrophils.

Free Radic. Biol. Med. 17(4) , 311-20, (1994)

PQQ, also called methoxatin, has been isolated from guinea-pig neutrophils. The organic cations diphenyleneiodonium (DPI) and diphenyliodonium (BPI) and the aromatic o-diamine 4,5-dimethylphenylenediamine (DIMPDA) sequester synthetic PQQ and inhibit its redox...

Rapid and sensitive determination of the intermediates of advanced glycation end products in the human nail by ultra-performance liquid chromatography with electrospray ionization time-of-flight mass spectrometry.

Anal. Biochem. 424(2) , 187-94, (2012)

The resolution of the intermediate advanced glycation end products (AGEs) in the human nail was carried out by the combination of 4,5-dimethyl-1,2-phenylenediamine (DMPD) derivatives and ultra-performance liquid chromatography with electrospray ionization tim...

A simple fluorometric determination of vitamin C.

Chem. Pharm. Bull. 46(9) , 1474-6, (1998)

A simple and accurate method for determination of vitamin C (ascorbic acid (AsA) and dehydroascorbic acid (DHA)) using 4,5-dimethyl-o-phenylenediamine (DMPD) was investigated. It was found that DMPD is a useful fluorescent reagent. The reaction product of DMP...

[Products in the fluorometric reaction of purines with 4,5-dimethyl-o-phenylenediamine after oxidation using N-bromosuccinimide].

Yakugaku Zasshi 110(10) , 776-82, (1990)

Twelve purines oxidized with 4,5-dimethyl-o-phenylenediamine (DMPD) was found to react with N-bromosuccinimide (NBS) to give fluorescent derivatives. In this paper, the identification of oxidation and fluorescent products have been described. In compliance wi...

Bull. Korean Chem. Soc. 15 , 1122, (1994)