Edelfosine

Edelfosine Structure
Edelfosine structure
Common Name Edelfosine
CAS Number 70641-51-9 Molecular Weight 523.726
Density N/A Boiling Point N/A
Molecular Formula C27H58NO6P Melting Point N/A
MSDS USA Flash Point N/A

Coculture of peripheral blood-derived mesenchymal stem cells and endothelial progenitor cells on strontium-doped calcium polyphosphate scaffolds to generate vascularized engineered bone.

Tissue Eng. Part A 21(5-6) , 948-59, (2015)

Vascularization of engineered bone tissue is critical for ensuring its survival after implantation and it is the primary factor limiting its clinical use. A promising approach is to prevascularize bone grafts in vitro using endothelial progenitor cells (EPC) ...

Differentiation of human umbilical cord matrix mesenchymal stem cells into neural-like progenitor cells and maturation into an oligodendroglial-like lineage.

PLoS ONE 9(10) , e111059, (2014)

Mesenchymal stem cells (MSCs) are viewed as safe, readily available and promising adult stem cells, which are currently used in several clinical trials. Additionally, their soluble-factor secretion and multi-lineage differentiation capacities place MSCs in th...

Knock-down of p300 decreases the proliferation and odontogenic differentiation potentiality of HDPCs.

Int. Endod. J. 48 , 976-85, (2015)

To investigate the role of p300 in the regulation of proliferation and odontogenic differentiation of human dental pulp cells (HDPCs).The recombinant lentiviral vector pshRNA-copGFP was used to knock-down p300 expression in HDPCs. Protein level of acetylated ...

A model of metabolic syndrome and related diseases with intestinal endotoxemia in rats fed a high fat and high sucrose diet.

PLoS ONE 9(12) , e115148, (2014)

We sought develop and characterize a diet-induced model of metabolic syndrome and its related diseases.The experimental animals (Spague-Dawley rats) were randomly divided into two groups, and each group was fed a different feed for 48 weeks as follows: 1) sta...

Effect of Nigella sativa fixed oil on ethanol toxicity in rats.

Iran. J. Basic Med. Sci. 17(12) , 1020-31, (2015)

This study was planned to appraise the protective effect of Nigella sativa fixed oil (NSO) against subchronic ethanol induced toxicity in rats.Studies were carried out on six groups of six animals each, including control (normal saline, gavage), ethanol (3 g/...

Transplantation of cultured dental pulp stem cells into the skeletal muscles ameliorated diabetic polyneuropathy: therapeutic plausibility of freshly isolated and cryopreserved dental pulp stem cells.

Stem Cell Res. Ther. 6 , 162, (2015)

Dental pulp stem cells (DPSCs) are mesenchymal stem cells located in dental pulp and are thought to be a potential source for cell therapy since DPSCs can be easily obtained from teeth extracted for orthodontic reasons. Obtained DPSCs can be cryopreserved unt...

Magnesium modulates the expression levels of calcification-associated factors to inhibit calcification in a time-dependent manner.

Exp. Ther. Med. 9(3) , 1028-1034, (2015)

Vascular calcification, a common complication in patients with chronic kidney disease, involves a variety of mechanisms associated with the regulation of calcification-associated factors. Previous clinical studies have indicated that magnesium is involved in ...

Multilineage co-culture of adipose-derived stem cells for tissue engineering.

J. Tissue Eng. Regen. Med. 9 , 826-37, (2015)

Stem cell interactions through paracrine cell signalling can regulate a range of cell responses, including metabolic activity, proliferation and differentiation. Moving towards the development of optimized tissue-engineering strategies with adipose-derived st...

Tumour-associated fibroblasts contribute to neoangiogenesis in human parathyroid neoplasia.

Endocr. Relat. Cancer 22(1) , 87-98, (2015)

Components of the tumour microenvironment initiate and promote cancer development. In this study, we investigated the stromal component of parathyroid neoplasia. Immunohistochemistry for alpha-smooth muscle actin (α-SMA) showed an abundant periacinar distribu...

The effects of dynamic compression on the development of cartilage grafts engineered using bone marrow and infrapatellar fat pad derived stem cells.

Biomed. Mater. 10 , 055011, (2015)

Bioreactors that subject cell seeded scaffolds or hydrogels to biophysical stimulation have been used to improve the functionality of tissue engineered cartilage and to explore how such constructs might respond to the application of joint specific mechanical ...