Dithioerythritol

Dithioerythritol Structure
Dithioerythritol structure
Common Name Dithioerythritol
CAS Number 6892-68-8 Molecular Weight 154.251
Density 1.3±0.1 g/cm3 Boiling Point 364.5±42.0 °C at 760 mmHg
Molecular Formula C4H10O2S2 Melting Point 82-86ºC
MSDS Chinese USA Flash Point 174.2±27.9 °C

Heterotrimeric NADH-oxidizing methylenetetrahydrofolate reductase from the acetogenic bacterium Acetobacterium woodii.

J. Bacteriol. 197(9) , 1681-9, (2015)

The methylenetetrahydrofolate reductase (MTHFR) of acetogenic bacteria catalyzes the reduction of methylene-THF, which is highly exergonic with NADH as the reductant. Therefore, the enzyme was suggested to be involved in energy conservation by reducing ferred...

Markers of mesterolone abuse in sulfate fraction for doping control in human urine.

J. Mass Spectrom. 50 , 1409-19, (2015)

This manuscript describes the direct detection of mesteroloe sulfo-conjugated metabolites by liquid chromatography/quadrupole/time of flight mass spectrometry (LC/Q/TOFMS) with special focus on evaluation of their retrospective detectability and their structu...

Proteomic analysis of the cytotoxic effects induced by the organogold(III) complex Aubipyc in cisplatin-resistant A2780 ovarian cancer cells: further evidence for the glycolytic pathway implication.

Mol. Biosyst. 11 , 1653-67, (2015)

The cellular alterations produced in cisplatin-resistant A2780 ovarian cancer cells (A2780/R) upon treatment with the cytotoxic organogold(III) complex Aubipyc were investigated in depth through a classical proteomic approach. We observed that A2780/R cell ex...

Surface properties of nanocrystalline TiO2 coatings in relation to the in vitro plasma protein adsorption.

Biomed. Mater. 10 , 045012, (2015)

This study reports on the selective adsorption of whole plasma proteins on hydrothermally (HT) grown TiO2-anatase coatings and its dependence on the three main surface properties: surface charge, wettability and roughness. The influence of the photo-activatio...

Proteomic analysis of lymphoblastoid cells from Nasu-Hakola patients: a step forward in our understanding of this neurodegenerative disorder.

PLoS ONE 9(12) , e110073, (2014)

Nasu-Hakola disease (NHD) is a recessively inherited rare disorder characterized by a combination of neuropsychiatric and bone symptoms which, while being unique to this disease, do not provide a rationale for the unambiguous identification of patients. These...

The impact of testosterone, tibolone and black cohosh on purified mammary and placental 17β-hydroxysteroid dehydrogenase type 1.

J. Enzyme Inhib. Med. Chem. 30 , 448-57, (2015)

Mammary and placental 17β-hydroxysteroid dehydrogenase type 1 (17βHSD1).To assess the impact of testosterone, tibolone, and black cohosh on purified mammary and placental 17βHSD1.17βHSD1 was purified from human mammary gland and placenta by column chromatogra...

A multi-platform metabolomics approach demonstrates changes in energy metabolism and the transsulfuration pathway in Chironomus tepperi following exposure to zinc.

Aquat. Toxicol. 162 , 54-65, (2015)

Measuring biological responses in resident biota is a commonly used approach to monitoring polluted habitats. The challenge is to choose sensitive and, ideally, stressor-specific endpoints that reflect the responses of the ecosystem. Metabolomics is a potenti...

Validation of a liquid chromatography-high-resolution mass spectrometry method for the analysis of ceftiofur in poultry muscle, kidneys and plasma: A unique accuracy profile for each and every matrix.

J. Chromatogr. A. 1407 , 119-29, (2015)

A robust, selective and specific liquid chromatography-high resolution mass spectrometry (LC-HRMS) method was developed for the quantification of total residues of ceftiofur, an antibiotic belonging to the 3rd generation cephalosporins in plasma, muscle and k...

Yeast Saccharomyces cerevisiae adiponectin receptor homolog Izh2 is involved in the regulation of zinc, phospholipid and pH homeostasis.

Metallomics 7 , 1338-51, (2015)

The functional link between zinc homeostasis and membrane-related processes, including lipid metabolism regulation, extends from yeast to humans, and has a likely role in the pathogenesis of diabetes. The yeast Izh2 protein has been previously implicated in z...

Efficient production of secreted staphylococcal antigens in a non-lysing and proteolytically reduced Lactococcus lactis strain.

Appl. Microbiol. Biotechnol. 98(24) , 10131-41, (2014)

Cell surface-exposed and secreted proteins are attractive targets for vaccination against pathogenic gram-positive bacteria. To obtain sufficient amounts of such antigens, efficient protein production platforms are needed. In this study, a pipeline for the pr...