eddp perchlorate
eddp perchlorate structure
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Common Name | eddp perchlorate | ||
|---|---|---|---|---|
| CAS Number | 66729-78-0 | Molecular Weight | 377.862 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H24ClNO4 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
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A rapid UPLC-MS/MS method for simultaneous determination of flunitrazepam, 7-aminoflunitrazepam, methadone and EDDP in human, rat and rabbit plasma.
Talanta 99 , 649-59, (2012) A simple, high-throughput, sensitive LC-ESI-MS/MS method is presented for the simultaneous determination of methadone (MET), flunitrazepam (FNZ) and their major metabolites, EDDP (2-ethilidene-1,5-dimethyl-3,3-diphenylpyrrolidone) and 7-aminoflunitrazepam (7-... |
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Drugs of abuse in wastewater and suspended particulate matter--further developments in sewage epidemiology.
Environ. Int. 48 , 28-38, (2012) This manuscript reports, for the first time, a monitoring study analysing wastewater and associated suspended particulate matter (SPM) to determine the concentration of drugs of abuse and metabolites in wastewater influent. The monitoring of SPM is crucial fo... |
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Methadone disposition in oral fluid during pharmacotherapy for opioid-dependence.
Forensic Sci. Int. 206(1-3) , 98-102, (2011) Oral fluid testing is widely used for detecting drug exposure, but data describing methadone and metabolites in oral fluid during pharmacotherapy for opioid-dependence are relatively limited.414 oral fluid specimens from 16 opioid-dependent pregnant women rec... |
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Evaluating the relationship of methadone concentrations and EDDP formation in chronic pain patients.
J. Anal. Toxicol. 36(4) , 239-49, (2012) Methadone is used to treat moderate to severe pain in patients not responsive to non-narcotic analgesics and for maintenance treatment of opioid addiction. Methadone is primarily metabolized by N-demethylation to an inactive metabolite 2-ethylidene-1,5-dimeth... |
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Methadone, cocaine, opiates, and metabolite disposition in umbilical cord and correlations to maternal methadone dose and neonatal outcomes.
Ther. Drug Monit. 33(4) , 443-52, (2011) The purpose was to explore methadone and 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine (EDDP) umbilical cord disposition, correlate with maternal methadone dose and neonatal outcomes, and evaluate the window of drug detection in umbilical cord of in utero... |
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Postmortem blood and tissue concentrations of R- and S-enantiomers of methadone and its metabolite EDDP.
Forensic Sci. Int. 226(1-3) , 254-60, (2013) Body fluids and tissues in 16 methadone (MTD)-associated fatalities were investigated to find out whether analysis of MTD and its metabolite 2-ethylidine-1,5-dimethyl-3,3-diphenylpyrrolidine (EDDP) following enantioselective separation of both compounds may a... |
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Quantification of methadone and its metabolite 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine in third instar larvae of Lucilia sericata (Diptera: Calliphoridae) using liquid chromatography-tandem mass spectrometry.
J. Anal. Toxicol. 34(7) , 374-80, (2010) Entomotoxicology studies the application of toxicological analysis on necrophageous insects present on human remains. This paper describes the development and validation of a sensitive liquid chromatography tandem mass spectrometry method for quantification o... |
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Effect of rifampin and nelfinavir on the metabolism of methadone and buprenorphine in primary cultures of human hepatocytes.
Drug Metab. Dispos. 37(12) , 2323-9, (2009) We tested the hypothesis that primary cultures of human hepatocytes could predict potential drug interactions with methadone and buprenorphine. Hepatocytes (five donors) were preincubated with dimethyl sulfoxide (DMSO) (vehicle), rifampin, or nelfinavir befor... |
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Genotoxicity assessment of ethylenediamine dinitrate (EDDN) and diethylenetriamine trinitrate (DETN)
Mutat. Res. 726(2) , 169-74, (2011) Highlights ► Ethylenediamine dinitrate and diethylenetriamine trinitrate are explosive compounds. ► A standard genetic toxicity battery was used to evaluate genotoxicity potentials. ► Ethylenediamine dinitrate was mutagenic only in strain TA 100. ► Diethylene... |
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Sweat testing to monitor drug exposure.
Ann. Clin. Lab. Sci. 43(1) , 22-30, (2013) It may be advantageous to use sweat, rather than blood or urine, to monitor individuals' drug exposure for the purposes of drug treatment programs, employment initiatives, and forensic investigations. Forty-eight patients receiving methadone at the Public Ser... |