H-Glu(OEt)-OH
H-Glu(OEt)-OH structure
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Common Name | H-Glu(OEt)-OH | ||
|---|---|---|---|---|
| CAS Number | 1119-33-1 | Molecular Weight | 175.182 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 326.5±37.0 °C at 760 mmHg | |
| Molecular Formula | C7H13NO4 | Melting Point | ~179 °C (dec.) | |
| MSDS | USA | Flash Point | 151.3±26.5 °C | |
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Enhanced group II mGluR-mediated inhibition of pain-related synaptic plasticity in the amygdala.
Mol. Pain 2 , 18, (2006) The latero-capsular part of the central nucleus of the amygdala (CeLC) is the target of the spino-parabrachio-amygdaloid pain pathway. Our previous studies showed that CeLC neurons develop synaptic plasticity and increased neuronal excitability in the kaolin/... |
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Place preference induced by nucleus accumbens amphetamine is impaired by local blockade of Group II metabotropic glutamate receptors in rats.
BMC Neurosci. 7 , 43, (2006) The nucleus accumbens (NAc) plays a critical role in amphetamine-produced conditioned place preference (CPP). In previous studies, NAc basal and amphetamine-produced DA transmission was altered by Group II mGluR agents. We tested whether NAc amphetamine CPP d... |
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Metabotropic glutamate receptors in the hippocampus and nucleus accumbens are involved in generating seizure-induced hippocampal gamma waves and behavioral hyperactivity.
Behav. Brain Res. 133(1) , 45-56, (2002) The involvement of metabotropic glutamate receptor (mGluR) subtypes in the generation of hippocampal EEG (30-100 Hz) and behaviors induced by a hippocampal afterdischarge (AD) was examined in freely behaving rats. A hippocampal AD induced an increase in gamma... |
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Blockade of group II, but not group I, mGluRs in the rat nucleus accumbens inhibits the expression of conditioned hyperactivity in an amphetamine-associated environment.
Behav. Brain Res. 191(1) , 62-6, (2008) Environmental stimuli associated with amphetamine (AMPH) can elicit conditioned locomotion in rats, and the nucleus accumbens (NAcc) is known to be important in this process. This study examined the contribution of metabotropic glutamate receptors (mGluRs) in... |
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Involvement of metabotropic glutamate receptors in ischemia-induced taurine release in the developing and adult hippocampus.
Neurochem. Res. 25(8) , 1067-72, (2000) Metabotropic glutamate receptors have recently been envisaged as involved in both potentiation and prevention of ischemic and excitotoxic neuronal damage. The release of the inhibitory amino acid taurine is markedly enhanced in ischemia in both the immature a... |
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Modulation of epileptiform burst frequency by the metabotropic glutamate receptor subtype mGluR3.
Epilepsy Res. 53(3) , 207-15, (2003) Spontaneous epileptiform burst activity occurs in acute hippocampal slice dentate granule cells perfused with 10mM potassium and 0.5mM calcium [J. Neurophys. 68 (1992) 2016]. We report that activation of the group II metabotropic glutamate receptor subtype 3 ... |
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Modulation of a spinal locomotor network by metabotropic glutamate receptors.
Eur. J. Neurosci. 26(8) , 2257-68, (2007) We have explored the potential involvement of the three main classes of metabotropic glutamate receptor in the modulation of a spinal locomotor network using tadpoles of the anuran amphibian Xenopus laevis. Selective activation of group I receptors in Xenopus... |
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Group II metabotropic glutamate receptors reduce excitatory but not inhibitory neurotransmission in rat barrel cortex in vivo.
Neuroscience 146(1) , 202-12, (2007) Group II metabotropic (mGlu) receptors are known to play an important role in regulating the release of excitatory transmitter in a number of brain areas. Previous experiments demonstrated that (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid (1S,3R-ACPD) de... |
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Antinociceptive effect of a group II metabotropic glutamate receptor antagonist in the thalamus of monoarthritic rats.
Neurosci. Lett. 296(1) , 25-8, (2000) Adult rats were rendered monoarthritic (MA) by injection of 50 microl of complete Freund's adjuvant (CFA) into the tibiotarsal joint. The ankle-bend (AB) test of nociception was performed in those animals before and during 60 min after the stereotaxic injecti... |
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Activation of group I metabotropic glutamate receptors depresses recurrent inhibition of motoneurons in the neonatal rat spinal cord in vitro.
Exp. Brain Res. 164(3) , 406-10, (2005) This study examined whether activation of group I metabotropic glutamate receptors (mGluRs) could modulate synaptic inhibition of spinal motoneurons in the neonatal rat isolated spinal cord. Recurrent inhibitory postsynaptic potentials (IPSPs) generated by Re... |