![]() Aprotinin acetate salt structure
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Common Name | Aprotinin acetate salt | ||
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CAS Number | 9087-70-1 | Molecular Weight | 6511.83000 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C284H432N84O79S7 | Melting Point | N/A | |
MSDS | USA | Flash Point | N/A |
Engineering of a Biomimetic Pericyte-Covered 3D Microvascular Network.
PLoS ONE 10 , e0133880, (2015) Pericytes enveloping the endothelium play an important role in the physiology and pathology of microvessels, especially in vessel maturation and stabilization. However, our understanding of fundamental pericyte biology is limited by the lack of a robust in vi... |
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SH2-PLA: a sensitive in-solution approach for quantification of modular domain binding by proximity ligation and real-time PCR.
BMC Biotechnol. 15 , 60, (2015) There is a great interest in studying phosphotyrosine dependent protein-protein interactions in tyrosine kinase pathways that play a critical role in many aspects of cellular function. We previously established SH2 profiling, a phosphoproteomic approach based... |
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Functional microRNA library screening identifies the hypoxamir miR-24 as a potent regulator of smooth muscle cell proliferation and vascularization.
Antioxid. Redox Signal. 21(8) , 1167-76, (2014) Smooth muscle cells (SMCs) are key components within the vasculature. Dependent on the stimulus, SMC can either be in a proliferative (synthetic) or differentiated state. Alterations of SMC phenotype also appear in several disease settings, further contributi... |
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Vitamin D Binding Protein Isoforms and Apolipoprotein E in Cerebrospinal Fluid as Prognostic Biomarkers of Multiple Sclerosis.
PLoS ONE 10 , e0129291, (2015) Multiple sclerosis (MS) is a multifactorial autoimmune disease of the central nervous system with a heterogeneous and unpredictable course. To date there are no prognostic biomarkers even if they would be extremely useful for early patient intervention with p... |
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Comparison of complexes formed by a crustacean and a vertebrate trypsin with bovine pancreatic trypsin inhibitor - the key to achieving extreme stability?
FEBS J. 280(22) , 5750-63, (2013) This paper provides evidence for the extremely high resistance of a complex of crayfish trypsin (CFT) and bovine pancreatic trypsin inhibitor (BPTI) against heating and chemical denaturing agents such as sodium dodecyl sulfate (SDS) and urea. To dissociate th... |
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Functional characterization of a slow and tight-binding inhibitor of plasmin isolated from Russell's viper venom.
Biochim. Biophys. Acta 1840(1) , 153-9, (2014) Snake venoms are rich in Kunitz-type protease inhibitors that may have therapeutic applications. However, apart from trypsin or chymotrypsin inhibition, the functions of most of these inhibitors have not been elucidated. A detailed functional characterization... |
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Lipid phosphate phosphohydrolase type 1 (LPP1) degrades extracellular lysophosphatidic acid in vivo.
Biochem. J. 419 , 611-8, (2009) LPA (lysophosphatidic acid) is a lipid mediator that stimulates cell proliferation and growth, and is involved in physiological and pathological processes such as wound healing, platelet activation, angiogenesis and the growth of tumours. Therefore defining t... |
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Tranexamic acid concentrations associated with human seizures inhibit glycine receptors.
J. Clin. Invest. 122(12) , 4654-66, (2012) Antifibrinolytic drugs are widely used to reduce blood loss during surgery. One serious adverse effect of these drugs is convulsive seizures; however, the mechanisms underlying such seizures remain poorly understood. The antifibrinolytic drugs tranexamic acid... |
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Antifibrinolytic drugs for acute traumatic injury.
Cochrane Database Syst. Rev. 12 , CD004896, (2012) Uncontrolled bleeding is an important cause of death in trauma victims. Antifibrinolytic treatment has been shown to reduce blood loss following surgery and may also be effective in reducing blood loss following trauma.To quantify the effects of antifibrinoly... |
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Antifibrinolytic agents in current anaesthetic practice.
Br. J. Anaesth. 111(4) , 549-63, (2013) Antifibrinolytic drugs have become almost ubiquitous in their use during major surgery when bleeding is expected or commonplace. Inhibition of the fibrinolytic pathway after tissue injury has been consistently shown to reduce postoperative or traumatic bleedi... |