Poly(N-isopropylacrylamide-co-methacrylic acid)
Poly(N-isopropylacrylamide-co-methacrylic acid) structure
|
Common Name | Poly(N-isopropylacrylamide-co-methacrylic acid) | ||
|---|---|---|---|---|
| CAS Number | 151954-97-1 | Molecular Weight | 199.24700 | |
| Density | N/A | Boiling Point | 225.1ºC at 760mmHg | |
| Molecular Formula | C10H17NO3 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 119.7ºC | |
|
The use of colloidal microgels as a (trans)dermal drug delivery system.
Int. J. Pharm. 292(1-2) , 137-47, (2005) A co-polymer of poly(N-isopropylacrylamide) (85%) co-butyl acrylate (10%) co-methacrylic acid (5%) (NIPAM/BA/MAA) (85/10/5) microgel was synthesised and investigated as a potential pH and temperature sensitive transdermal delivery device. Three compounds havi... |
|
|
Synthesis of novel metal sulfide-polymer composite microspheres exhibiting patterned surface structures.
Langmuir 20(1) , 263-5, (2004)
|
|
|
On the stability of insulin delivered through a new glucose-responsive polymeric composite membrane.
J. Pharm. Pharmacol. 56(5) , 611-20, (2004) A new glucose-responsive polymeric composite membrane that provided pulsatile insulin release was developed in our laboratory previously. To develop a clinically useful insulin delivery system, this study was designed to investigate factors influencing insuli... |
|
|
Thermoresponsive polymer colloids for drug delivery and cancer therapy.
Macromol. Biosci. 11(12) , 1722-34, (2011) Many difficulties in treating cancer arise from the problems in directing highly cytotoxic agents to the deseased tissues, cells and intracellular compartments. Many drug delivery systems have been devised to address this problem, including those that show a ... |
|
|
Dependence of copolymer composition, swelling history, and drug concentration on the loading of diltiazem hydrochloride (DIL.HCl) into poly[(N-isopropylacrylamide)-co-(methacrylic acid)] hydrogels and its release behaviour from hydrogel slabs.
J. Control. Release 102(3) , 595-606, (2005) The loading of an antihypertensive cationic drug, diltiazem hydrochloride (DIL.HCl), into poly(N-isopropylacrylamide) [P(N-iPAAm)], poly(methacrylic acid) [P(MAA)], and their poly[(N-isopropylacrylamide)-co-(methacrylic acid)] P[(N-iPAAm)-co-(MAA)] hydrogels ... |
|
|
Toward modeling thermoresponsive polymer networks: a molecular dynamics simulation study of N-isopropyl acrylamide co-oligomers.
J. Phys. Chem. B 114(25) , 8301-12, (2010) Polymer microgels of poly(vinyl alcohol)/poly(methacrylate-co-N-isopropyl acrylamide) showed a thermoresponsive behavior, suitable for application in drug delivery (Biomacromolecules 2009, 10, 1589). In this work molecular dynamics (MD) methods were used to e... |
|
|
Effect of layer-by-layer confinement of polypeptides and polysaccharides onto thermoresponsive microgels: A comparative study
J. Colloid. Interface Sci. 347(1) , 79-89, (2010) A comparative study of the layer-by-layer assembly of polypeptides (PLL/PGA) and polysaccharides (CHIT/DEX) onto soft and porous thermoresponsive P(NiPAM-co-MAA) microgel was undertaken by dynamic light scattering and electrophoretic measurements. |
|
|
Capturing of acidic macromolecules from biological samples using a temperature-responsive polymer modified with poly-l-lysine.
Analyst 129(5) , 421-7, (2004) We synthesized a temperature-responsive polymer, N-(isopropylacrylamide)-methacrylic acid copolymer, to which poly-l-lysine was introduced. The synthesized polymer as well as the parent polymer showed reversible soluble-insoluble changes in response to temper... |
|
|
The influence of the copolymer composition on the diltiazem hydrochloride release from a series of pH-sensitive poly[(N-isopropylacrylamide)-co-(methacrylic acid)] hydrogels.
AAPS PharmSciTech 5(2) , e33, (2004) A series of poly[(N-isopropylacrylamide)-co-(methacrylic acid)] (P[(N-iPAAm)-co-(MAA)]) hydrogels was investigated to determine the composition that exhibits a better pH-modulated release of diltiazem hydrochloride (DIL.HCl). For this purpose hydrogel slabs w... |
|
|
Temperature and pH-responsive polymeric composite membranes for controlled delivery of proteins and peptides.
Biomaterials 25(22) , 5281-91, (2004) This work was focused on the investigation of temperature and pH-responsive polymeric composite membranes and their permeability to proteins and peptides in response to environmental stimuli. The composite membranes were prepared from nanoparticles of poly(N-... |