![]() Phenylac-Gly-Lys-OH structure
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Common Name | Phenylac-Gly-Lys-OH | ||
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CAS Number | 113969-25-8 | Molecular Weight | 321.37200 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C16H23N3O4 | Melting Point | N/A | |
MSDS | Chinese USA | Flash Point | N/A |
3-hydroxykynurenine-mediated modification of human lens proteins: structure determination of a major modification using a monoclonal antibody.
J. Biol. Chem. 280 , 22154-22164, (2005) Tryptophan can be oxidized in the eye lens by both enzymatic and non-enzymatic mechanisms. Oxidation products, such as kynurenines, react with proteins to form yellow-brown pigments and cause covalent cross-linking. We generated a monoclonal antibody against ... |
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Elucidation of a novel polypeptide cross-link involving 3-hydroxykynurenine.
Biochemistry 38 , 11455-11464, (1999) 3-Hydroxykynurenine, a metabolite of tryptophan, is a powerful antioxidant and neurotoxin. The neurotoxicity results from the oxidation of 3-hydroxykynurenine, and hydroxyl radicals, formed via H(2)O(2), may also be implicated [Okuda, S., Nishiyama, N., Saito... |
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Polypeptide modification and cross-linking by oxidized 3-hydroxykynurenine.
Biochemistry 39 , 16176-16184, (2000) 3-Hydroxykynurenine (3OHKyn) is present in the mammalian lens as a UV filter and is formed from kynurenine in the tryptophan metabolic pathway. 3OHKyn is a readily autoxidized o-aminophenol which binds to proteins in vitro. The lens, particularly its central ... |
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Nosho, Y. and Ohfuji, T.
Chem. Eng. News 68(2) , 25, (1990)
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