cis-4,7,10,13,16,19-Docosahexaenoic-21,21,22,22,22-d5 acid

cis-4,7,10,13,16,19-Docosahexaenoic-21,21,22,22,22-d5 acid Structure
cis-4,7,10,13,16,19-Docosahexaenoic-21,21,22,22,22-d5 acid structure
Common Name cis-4,7,10,13,16,19-Docosahexaenoic-21,21,22,22,22-d5 acid
CAS Number 1197205-71-2 Molecular Weight 333.52
Density 0.9±0.1 g/cm3 Boiling Point 446.7±24.0 °C at 760 mmHg
Molecular Formula C22H27D5O2 Melting Point N/A
MSDS USA Flash Point 343.4±18.0 °C

Chiral chromatography-tandem mass spectrometry applied to the determination of pro-resolving lipid mediators.

J. Chromatogr. A. 1360 , 150-63, (2014)

Pro-resolving lipid mediators are a class of endogenously synthesized molecules derived from different fatty acids, such as arachidonic, docosahexaenoic or eicosapentaenoic acid, which are derived into four different product families: lipoxins, resolvins, mar...

Serum levels of lipid metabolites in age-related macular degeneration.

FASEB J. 29 , 4579-88, (2015)

Age-related macular degeneration (AMD) is a neurodegenerative disease that causes adult-onset blindness. There are 2 forms of this progressive disease: wet and dry. Currently there is no cure for AMD, but several treatment options have started to emerge makin...

Neuroprotectin/protectin D1: endogenous biosynthesis and actions on diabetic macrophages in promoting wound healing and innervation impaired by diabetes.

Am. J. Physiol. Cell Physiol. 307(11) , C1058-67, (2014)

Dysfunction of macrophages (MΦs) in diabetic wounds impairs the healing. MΦs produce anti-inflammatory and pro-resolving neuroprotectin/protectin D1 (NPD1/PD1, 10R,17S-dihydroxy-docosa-4Z,7Z,11E,13E,15Z,19Z-hexaenoic acid); however, little is known about endo...

N-3 PUFA increase bioavailability and function of endothelial progenitor cells.

Food Funct. 5(8) , 1881-90, (2014)

Recent data suggest that n-3 PUFA exert beneficial effects on endothelial progenitor cell (EPC) biology. We sought to investigate whether these effects might be mediated by enhanced EPC in vitro function and/or in vivo bioavailability.CACs and late-outgrowth ...