Dimethylprotoporphyrin IX dimethyl ester
Dimethylprotoporphyrin IX dimethyl ester structure
|
Common Name | Dimethylprotoporphyrin IX dimethyl ester | ||
|---|---|---|---|---|
| CAS Number | 5522-66-7 | Molecular Weight | 590.711 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 1017.0±65.0 °C at 760 mmHg | |
| Molecular Formula | C36H38N4O4 | Melting Point | 225-228ºC | |
| MSDS | Chinese USA | Flash Point | 568.8±34.3 °C | |
|
Observation of heme transfer from cytochrome b5 to DNA aptamer.
Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 96 , 365-9, (2012) Heme transfer is commonly observed from one heme protein to the other such as from cytochrome b(5) (cyt b(5)) to apo-myoglobin. In this study, instead of to another heme protein, we observed the heme transfer from wild-type (WT) cyt b(5), H39C cyt b(5) with h... |
|
|
Direct electrochemistry and spectroelectrochemistry of osmium substituted horseradish peroxidase.
Bioelectrochemistry 76(1-2) , 28-33, (2009) In this contribution the substitution of the central protoporphyrin IX iron complex of horseradish peroxidase by the respective osmium porphyrin complex is described. The direct electrochemical reduction of the Os containing horseradish peroxidase (OsHRP) was... |
|
|
Comparison of binding ability and location of two mesoporphyrin derivatives in liposomes explored with conventional and site-selective fluorescence spectroscopy.
J. Phys. Chem. B 116(32) , 9644-52, (2012) Application of porphyrins as photosensitizers is based on their light-triggered generation of reactive oxygen species (ROS) that may cause oxidative tissue damage and ultimately kill cells. Cellular membranes are the action grounds of many sensitizers due to ... |
|
|
Design, synthesis, and in vitro photodynamic activities of benzochloroporphyrin derivatives as tumor photosensitizers.
Bioorg. Med. Chem. Lett. 18(1) , 293-7, (2008) Novel benzochloroporphyrin derivatives (BCPDs) were designed, synthesized, and characterized. In vitro dark cytotoxicity and photodynamic efficacy of BCPDs were evaluated by MTT assay on human hepatoma BEL-7402 cells. The experimental results showed that BCPD... |
|
|
[Accessibility of porphyrin macrocycle in myoglobin at various pH levels. Fluorescence study of the porphyrin-globin complex].
Mol. Biol. (Mosk.) 20(1) , 138-45, (1986) The fluorescent properties of the complexes of apoMb-PPIX and dimethyl-PPIX were studied in a wide range of pH and ionic strength. The quenching of fluorescence of PPIX in the complex by I- is shown to be of dynamic type Increasing of the Stern--Volmer consta... |
|
|
[Effect of oxygen on the irreversible radiochemical transformations of protoporphyrin in 2n. H2SO4].
Radiobiologiia 26(5) , 598-603, (1986) The mechanism of the inverse oxygen effect in the irreversible radiation-induced chemical alterations in protoporphyrin in sulfuric acid solution was investigated. The decrease of the molecular decay yield was shown to associate with the ability of oxygen to ... |
|
|
Photodegradation of protoporphyrin-dimethylester in solution and in organized environments.
Int. J. Radiat. Biol. 64(5) , 475-84, (1993) The degradation of sensitizers used in photodynamic therapy (PDT) involves photooxidation either by molecular oxygen or by oxygen intermediates which leads to hydroxyaldehyde and formyl products or to ring opening. Our investigations focused on the spectrosco... |
|
|
A study comparing endogenous protoporphyrin IX induced by 5-ALA and ALA-methyl ester with exogenous PpIX and PpIX dimethyl ester in photodynamic diagnosis of human nasopharyngeal carcinoma xenografts.
Int. J. Oncol. 29(4) , 997-1002, (2006) 5-Aminolevulinic acid (5-ALA) and its esters have been under intense investigation to enhance the endogenous production of protoporphyrin IX (PpIX) in tumour cells for the purpose of photodynamic diagnosis. In this study we have investigated the use of exogen... |
|
|
Enhanced transdermal transport by electroporation using anionic lipids.
J. Control. Release 82(2-3) , 399-405, (2002) Transdermal drug delivery is an attractive approach for either local or systemic treatment in medicine. In the last decade, different active transdermal delivery methods have been further investigated such as cationic liposomal delivery and electroporation-en... |
|
|
Solvent effect on MCD of Fe(III) heme complexes: magnetic circular dichroism spectra of five-coordinated high-spin iron(III) protoporphyrin-IX-dimethylester in the visible region and their environmental effect. A characterization of the visible electronic transitions in Fe(III) high-spin porphyrins.
J. Inorg. Biochem. 35(4) , 305-17, (1989) Magnetic circular dichroism (MCD) spectra were observed to characterize the nature of the visible bands for high-spin Fe(III) protoheme derivatives with p-nitrothiophenolate, p-nitrophenolate, and methoxy anion as the fifth ligands in several solvents. The vi... |