3-(2-Fluorophenyl)acrylic acid

3-(2-Fluorophenyl)acrylic acid Structure
3-(2-Fluorophenyl)acrylic acid structure
Common Name 3-(2-Fluorophenyl)acrylic acid
CAS Number 451-69-4 Molecular Weight 166.149
Density 1.3±0.1 g/cm3 Boiling Point 281.6±15.0 °C at 760 mmHg
Molecular Formula C9H7FO2 Melting Point 178-180 °C(lit.)
MSDS Chinese USA Flash Point 124.1±20.4 °C

(S,E)-N-[1-(3-heteroarylphenyl)ethyl]-3-(2-fluorophenyl)acrylamides: synthesis and KCNQ2 potassium channel opener activity.

Bioorg. Med. Chem. Lett. 15(2) , 363-6, (2005)

Replacement of the morpholinyl moiety in (S,E)-N-[1-(3-morpholinophenyl)ethyl]-3-phenylacrylamide (1) with heteroaryl groups led to the identification of (S,E)-N-1-[3-(6-fluoropyridin-3-yl)phenyl]ethyl-3-(2-fluorophenyl)acrylamide (5) as a potent KCNQ2 potass...