![]() Methyl glutarate structure
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Common Name | Methyl glutarate | ||
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CAS Number | 1119-40-0 | Molecular Weight | 160.168 | |
Density | 1.1±0.1 g/cm3 | Boiling Point | 211.2±0.0 °C at 760 mmHg | |
Molecular Formula | C7H12O4 | Melting Point | −13 °C(lit.) | |
MSDS | USA | Flash Point | 103.3±0.0 °C |
Mixture risk assessment: a case study of Monsanto experiences.
Food Chem. Toxicol. 34(11-12) , 1139-45, (1996) Monsanto employs several pragmatic approaches for evaluating the toxicity of mixtures. These approaches are similar to those recommended by many national and international agencies. When conducting hazard and risk assessments, priority is always given to usin... |
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Reproduction study with dibasic esters following inhalation in the rat.
Drug Chem. Toxicol. 21(3) , 253-67, (1998) Groups of 20 male and 20 female Crl:CD(SD)BR rats were exposed to Dibasic Esters (DBE) at concentrations of 0 (control), 0.16, 0.40 (maximum attainable vapor), or 1.0 mg/L (aerosol). Exposures were conducted for 6 hours/day, 5 days/week for 14 weeks (pre-bree... |
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Carboxylesterase-dependent cytotoxicity of dibasic esters (DBE) in rat nasal explants.
Toxicol. Appl. Pharmacol. 107(2) , 285-301, (1991) Dibasic esters (DBE) are a solvent mixture of dimethyl adipate (DMA), dimethyl glutarate (DMG), and dimethyl succinate (DMS) used in the paint and coating industry. Subchronic inhalation toxicity studies have demonstrated that DBE induce a mild degeneration o... |
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Metabolism of dibasic esters by rat nasal mucosal carboxylesterase.
Drug Metab. Dispos. 19(1) , 124-9, (1991) Inhalation exposure of rats to dibasic esters revealed lesions of the nasal olfactory epithelium similar to those observed with other ester solvents. Female rats are more sensitive to these effects than are male rats. It has been proposed that carboxylesteras... |
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Deposition of dibasic esters in the upper respiratory tract of the male and female Sprague-Dawley rat.
Toxicol. Appl. Pharmacol. 108(3) , 538-46, (1991) Inhalation exposure of the male and female rat to high concentrations of a mixture of the dibasic esters dimethyl succinate (DMS), dimethyl glutarate (DMG), and dimethyl adipate (DMA) results in mild olfactory toxicity. This response is thought to be due to t... |
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L-glutamate diethyl ester and deaminated analogues as excitatory amino acid antagonists in rat cerebral cortex.
Br. J. Pharmacol. 104(2) , 445-51, (1991) 1. The effects of L-glutamate diethyl ester (GDEE) HCl, glutarate diethyl ester (GlrDEE) and glutarate dimethyl ester (GlrDME) on depolarizing responses to alpha-amino-3-hydroxy-5- methyl-4-isoxazolepropionate (AMPA), kainate (Kain), N-methyl-D-aspartate (NMD... |
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Developmental toxicity of dibasic esters by inhalation in the rat.
Drug Chem. Toxicol. 18(4) , 295-314, (1995) Dibasic esters (DBE) are a mixture of 3 carboxylic acid esters which are used in the paint and coatings industry. In this study, groups of pregnant Crl:CD BR rats were exposed to either 0.16, 0.4, or 1.0 mg DBE/L by inhalation for 6 hr/day from Days 7 through... |