5-Carboxyfluorescein Diacetate
5-Carboxyfluorescein Diacetate structure
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Common Name | 5-Carboxyfluorescein Diacetate | ||
|---|---|---|---|---|
| CAS Number | 79955-27-4 | Molecular Weight | 460.389 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 693.1±55.0 °C at 760 mmHg | |
| Molecular Formula | C25H16O9 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 241.9±25.0 °C | |
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Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
J. Med. Chem. 51 , 3275-87, (2008) The chemical space of registered oral drugs was explored for inhibitors of the human multidrug-resistance associated protein 2 (MRP2; ABCC2), using a data set of 191 structurally diverse drugs and drug-like compounds. The data set included a new reference set... |
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Phylloxera (Daktulosphaira vitifoliae Fitch) alters the carbohydrate metabolism in root galls to allowing the compatible interaction with grapevine (Vitis ssp.) roots.
Plant Sci. 234 , 38-49, (2015) Gall forming phylloxera may compete for nutrients with meristematic tissues and develop heterotrophic structures that act as carbon sinks. In this work, we studied the underlying starch metabolism, sink-source translocation of soluble sugars towards and withi... |
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Upregulation of Multidrug Resistance-Associated Protein 1 by Allyl Isothiocyanate in Human Bronchial Epithelial Cell: Involvement of c-Jun N-Terminal Kinase Signaling Pathway.
Oxid. Med. Cell. Longev. 2015 , 903782, (2015) Multidrug resistance-associated protein 1 (MRP1) plays a protective role in the etiology and progression of chronic obstructive pulmonary disease (COPD) which results from oxidative stress and inflammation of lung injury. The lower functional MRP1 activity is... |
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Triggering enzymatic activity with force.
Nano Lett. 9(9) , 3290-5, (2009) Integrating single molecule force spectroscopy with fluorescence-based techniques allows the manipulation of an enzyme with a periodic stretching and relaxation protocol while simultaneously monitoring its catalytic activity. After releasing the stretching fo... |
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Fabrication of Collagen Gel Hollow Fibers by Covalent Cross-Linking for Construction of Bioengineering Renal Tubules.
ACS Appl. Mater. Interfaces 7 , 19789-97, (2015) Collagen, the most used natural biomacromolecule, has been extensively utilized to make scaffolds for cell cultures in tissue engineering, but has never been fabricated into the configuration of a hollow fiber (HF) for cell culture due to its poor mechanical ... |
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Apoptosis-inducing effects of Melissa officinalis L. essential oil in glioblastoma multiforme cells.
Cancer Invest. 32(6) , 226-35, (2014) Current therapies for glioblastoma multiforme (GBM) are not effective. This study investigated the activity of the M. officinalis essential oil (EO) and its major component (citral) in GBM cell lines. Both EO and citral decreased the viability and induced apo... |
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Role of intestinal bacteria in gliadin-induced changes in intestinal mucosa: study in germ-free rats.
PLoS ONE 6(1) , e16169, (2011) Celiac disease (CD) is a chronic inflammatory disorder of the small intestine that is induced by dietary wheat gluten proteins (gliadins) in genetically predisposed individuals. The overgrowth of potentially pathogenic bacteria and infections has been suggest... |
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Clearance of acute myeloid leukemia by haploidentical natural killer cells is improved using IL-2 diphtheria toxin fusion protein.
Blood 123(25) , 3855-63, (2014) Haploidentical natural killer (NK) cell infusions can induce remissions in some patients with acute myeloid leukemia (AML) but regulatory T-cell (Treg) suppression may reduce efficacy. We treated 57 refractory AML patients with lymphodepleting cyclophosphamid... |
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Enhanced dendritic cell-based immunotherapy using low-dose cyclophosphamide and CD25-targeted antibody for transplanted Lewis lung carcinoma cells.
J. Immunother. 38(3) , 107-15, (2015) Regulatory T cells (Tregs) is one of the main obstacles to the success of cancer immunotherapy. The effect of dendritic cell (DC)-based immunotherapy can be attenuated by immune suppressive functions of Tregs. We used a CD25-targeted antibody and low-dose cyc... |
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Design of 3D printed insert for hanging culture of Caco-2 cells.
Biofabrication 7(1) , 015003, (2014) A Caco-2 cell culture on Transwell, an alternative testing to animal or human testing used in evaluating drug intestinal permeability, incorrectly estimated the absorption of actively transported drugs due to the low expression of membrane transporters. Simil... |