Nile Red
Nile Red structure
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Common Name | Nile Red | ||
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| CAS Number | 7385-67-3 | Molecular Weight | 318.369 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 484.7±45.0 °C at 760 mmHg | |
| Molecular Formula | C20H18N2O2 | Melting Point | 203-205 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 246.9±28.7 °C | |
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Acoustic Cluster Therapy (ACT)--A novel concept for ultrasound mediated, targeted drug delivery.
Int. J. Pharm. 495 , 1019-27, (2015) A novel approach for ultrasound (US) mediated drug delivery - Acoustic Cluster Therapy (ACT) - is proposed, and basic characteristics of the ACT formulation are elucidated. The concept comprises administration of free flowing clusters of negatively charged mi... |
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High-fat diet-induced adiposity, adipose inflammation, hepatic steatosis and hyperinsulinemia in outbred CD-1 mice.
PLoS ONE 10(3) , e0119784, (2015) High-fat diet (HFD) has been applied to a variety of inbred mouse strains to induce obesity and obesity related metabolic complications. In this study, we determined HFD induced development of metabolic disorders on outbred female CD-1 mice in a time dependen... |
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microRNA-320/RUNX2 axis regulates adipocytic differentiation of human mesenchymal (skeletal) stem cells.
Cell Death Dis. 5 , e1499, (2014) The molecular mechanisms promoting lineage-specific commitment of human mesenchymal (skeletal or stromal) stem cells (hMSCs) into adipocytes (ADs) are not fully understood. Thus, we performed global microRNA (miRNA) and gene expression profiling during adipoc... |
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AMPK activation promotes lipid droplet dispersion on detyrosinated microtubules to increase mitochondrial fatty acid oxidation.
Nat. Commun. 6 , 7176, (2015) Lipid droplets (LDs) are intracellular organelles that provide fatty acids (FAs) to cellular processes including synthesis of membranes and production of metabolic energy. While known to move bidirectionally along microtubules (MTs), the role of LD motion and... |
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Neutral lipid alterations in human herpesvirus 8-infected HUVEC cells and their possible involvement in neo-angiogenesis.
BMC Microbiol. 15 , 74, (2015) Human Herpesvirus 8 (HHV8), the causative agent of Kaposi's sarcoma, induces an intense modification of lipid metabolism and enhances the angiogenic process in endothelial cells. In the present study, neutral lipid (NL) metabolism and angiogenesis were invest... |
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High-density lipoprotein contribute to G0-G1/S transition in Swiss NIH/3T3 fibroblasts.
Sci. Rep. 5 , 17812, (2015) High density lipoproteins (HDLs) play a crucial role in removing excess cholesterol from peripheral tissues. Although their concentration is lower during conditions of high cell growth rate (cancer and infections), their involvement during cell proliferation ... |
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Analysis of the pretreatment effect of ethanol on the stratum corneum- and hair follicular-penetration of drugs using the hair follicle-plugging method.
Chem. Pharm. Bull. 62(6) , 578-85, (2014) The hair follicle-plugging method was used to analyze the effects of EtOH on skin permeation pathways.In vitro permeation experiments were performed on 4 model drugs [isosorbide mononitrate (ISMN), ionized lidocaine (ionized LC), fluorescein (FL), and fluores... |
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Spectrally resolved fluorescence lifetime imaging of Nile red for measurements of intracellular polarity.
J. Biomed. Opt. 20 , 096002, (2015) Spectrally resolved confocal microscopy and fluorescence lifetime imaging have been used to measure the polarity of lipid-rich regions in living HeLa cells stained with Nile red. The emission peak from the solvatochromic dye in lipid droplets is at a shorter ... |
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Fluorescent labeling of proteins with nile red and 2-methoxy-2,4-diphenyl-3(2H)-furanone: physicochemical basis and application to the rapid staining of sodium dodecyl sulfate polyacrylamide gels and Western blots.
Electrophoresis 22(5) , 874-80, (2001) The fluorescent hydrophobic dye Nile red allows the rapid, sensitive, and general staining of proteins in sodium dodecyl sulfate (SDS)-polyacrylamide gels. Nile red staining does not preclude further electroblotting of protein bands onto polyvinylidene difluo... |
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The importance of the interaction between hepatocyte and hepatic stellate cells in fibrogenesis induced by fatty accumulation.
Exp. Mol. Pathol. 98(1) , 85-92, (2015) Non-alcoholic fatty liver disease is characterized by an initial accumulation of triglycerides that can progress to non-alcoholic steatohepatitis, which can ultimately evolve to cirrhosis and hepatocellular carcinoma. Hepatic stellate cells play a key role in... |