2-(Trifluoromethyl)benzamide

2-(Trifluoromethyl)benzamide Structure
2-(Trifluoromethyl)benzamide structure
Common Name 2-(Trifluoromethyl)benzamide
CAS Number 360-64-5 Molecular Weight 189.135
Density 1.3±0.1 g/cm3 Boiling Point 247.3±40.0 °C at 760 mmHg
Molecular Formula C8H6F3NO Melting Point 160-164 °C(lit.)
MSDS Chinese USA Flash Point 103.4±27.3 °C

Thyroid tumor formation in the male mouse induced by fluopyram is mediated by activation of hepatic CAR/PXR nuclear receptors.

Regul Toxicol Pharmacol 70(3) , 673-80, (2015)

Fluopyram, a broad spectrum fungicide, caused an increased incidence of thyroid follicular cell (TFC) adenomas in males at the highest dose evaluated (750ppm equating to 105mg/kg/day) in the mouse oncogenicity study. A series of short-term mechanistic studies...