trans-Cyclohexane-1,2-diol
trans-Cyclohexane-1,2-diol structure
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Common Name | trans-Cyclohexane-1,2-diol | ||
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| CAS Number | 1460-57-7 | Molecular Weight | 116.158 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 236.7±8.0 °C at 760 mmHg | |
| Molecular Formula | C6H12O2 | Melting Point | 101-104 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 114.3±13.0 °C | |
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Heterogeneity and Bipotency of Astroglial-Like Cerebellar Progenitors along the Interneuron and Glial Lineages.
J. Neurosci. 35 , 7388-402, (2015) Cerebellar GABAergic interneurons in mouse comprise multiple subsets of morphologically and neurochemically distinct phenotypes located at strategic nodes of cerebellar local circuits. These cells are produced by common progenitors deriving from the ventricul... |
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Effect of ethanol on the urinary excretion of cyclohexanol and cyclohexanediols, biomarkers of the exposure to cyclohexanone, cyclohexane and cyclohexanol in humans.
Scand. J. Work. Environ. Health 25(3) , 233-7, (1999) This study explored the acute effect of ethanol (EtOH) on the urinary excretion of cyclohexanol (CH-ol), 1,2- and 1,4-cyclohexanediol (CH-diol), biomarkers of exposure to important solvents, and chemical intermediates cyclohexanone (CH-one), cyclohexane (CH) ... |
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Tin(II) chloride catalyzed reactions of diazodiphenylmethane with vicinal diols in an aprotic solvent. The reactions with cis- and trans-1,2-cyclohexanediols and 1,2-propanediol.
Carbohydr. Res. 338(9) , 963-8, (2003) The paper reports the tin(II) chloride catalyzed reactions of diazodiphenylmethane with the cis- and trans-1,2-cyclohexanediols and R,S-1,2-propanediol in 1,2-dimethoxyethane and the identification of the monodiphenylmethyl ethers formed. The catalyst is show... |
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Biological monitoring of occupational exposure to cyclohexane by urinary 1,2- and 1,4-cyclohexanediol determination.
Int. Arch. Occup. Environ. Health 72(2) , 115-20, (1999) This article reports the results obtained with the biological and environmental monitoring of occupational exposure to cyclohexane using 1,2-cyclohexanediol (1,2-DIOL) and 1,4-DIOL in urine. The kinetic profile of 1,2-DIOL in urine suggested by a physiologica... |
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Expression of benzene dioxygenase from Pseudomonas putida ML2 in cis-1,2-cyclohexanediol-degrading pseudomonads.
Appl. Microbiol. Biotechnol. 55(6) , 721-6, (2001) Benzene dioxygenase (BDO; EC 1.14.12.3) from Pseudomonas putida ML2 dihydroxylates benzene to produce cis-1,2-dihydroxy-cyclohexa-3,5-diene. As well as oxidising benzene and toluene, cell-free extracts of Escherichia coli JM109 expressing recombinant BDO oxid... |
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Insight into acid-mediated asymmetric spirocyclization in the presence of a chiral diol.
Chem. Pharm. Bull. 48(10) , 1536-40, (2000) Asymmetric spirocyclization based on intramolecular conjugate addition using a combination of a Lewis acid and an optically active cyclohexane-1,2-diol has been studied in connection with 1) the effect of substituents on the cyclohexane-1,2-diol and 2) the ef... |
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Oxidation of cyclohexanediol derivatives with 12-tungstophosphoric acid-hydrogen peroxide system.
J. Oleo Sci. 58(6) , 323-8, (2009) Oxidation of cyclohexanediol derivatives with 12-tungstophospholic acid-hydrogen peroxide system was investigated focusing on a reaction mechanism in the preparation of dicarboxylic acids from olefin because oxidative cleavage of vicinal diols would be a rate... |
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Assessment of the nuclear pore dilating agent trans-cyclohexane-1,2-diol in differentiated airway epithelium.
J. Gene Med. 14(7) , 491-500, (2012) The nuclear membrane of differentiated airway epithelial cells is a significant barrier for nonviral vectors. Trans-cyclohexane-1,2-diol (TCHD) is an amphipathic alcohol that has been shown to collapse nuclear pore cores and allow the uptake of macromolecules... |
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Absence of interactive effects of trans-1,2-cyclohexanediol, a major metabolite of the side-chain of candesartan cilexetil, on digoxin-induced arrhythmias in dogs.
J. Pharmacol. Sci. 92(4) , 387-99, (2003) trans-1,2-Cyclohexanediol, the major metabolite of the cilexetil moiety of candesartan cilexetil (CC), has been reported to have potent pro-arrhythmic effects in dogs with congestive heart failure (CHF), especially when co-administered with digoxin. To verify... |
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New strategies for nucleic acid delivery to conquer cellular and nuclear membranes.
J. Control. Release 132(3) , 279-88, (2008) After administration to the body, nucleic acid containing nanoparticles (NANs) need to cross several extra- and intracellular barriers to reach the cytoplasm or nucleus of the target cells. In the last decade several groups tried to overcome these barriers by... |