Bongkrekic acid
Bongkrekic acid structure
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Common Name | Bongkrekic acid | ||
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| CAS Number | 11076-19-0 | Molecular Weight | 486.59700 | |
| Density | 1.114g/cm3 | Boiling Point | 715.1ºC at 760mmHg | |
| Molecular Formula | C28H38O7 | Melting Point | 50-60° | |
| MSDS | Chinese USA | Flash Point | 231ºC | |
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Changes in mitochondrial membrane potential during staurosporine-induced apoptosis in Jurkat cells.
FEBS Lett. 475 , 267, (2000) Cytochrome c release from mitochondria is central to apoptosis, but the events leading up to it are disputed. The mitochondrial membrane potential has been reported to decrease, increase or remain unchanged during cytochrome c release. We measured mitochondri... |
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BCL-2 family members and the mitochondria in apoptosis.
Genes Dev. 13 , 1899, (1999)
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Hydrogen peroxide-induced apoptosis is CD95-independent, requires the release of mitochondria-derived reactive oxygen species and the activation of NF-kappaB.
Oncogene 18 , 747, (1999) Reactive oxygen species (ROS) play an important role in cell death induced by many different stimuli. This study shows that hydrogen peroxide-induced apoptosis in T-cells did not require tyrosine kinase p561ck, phosphatase CD45, the CD95 receptor and its asso... |
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Ethanol potentiates tumor necrosis factor-alpha cytotoxicity in hepatoma cells and primary rat hepatocytes by promoting induction of the mitochondrial permeability transition.
Hepatology 31 , 1141, (2000) In the present study, tumor necrosis factor-alpha (TNF-alpha) cytotoxicity is shown to be potentiated by ethanol exposure in vitro in the human hepatoma cell line, HepG2, and in rat primary hepatocytes. Exposure of HepG2 cells and primary hepatocytes for 48 h... |
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Antiapoptosis chemicals prolong productive lifetimes of mammalian cells upon Sindbis virus vector infection.
Biotechnol. Bioeng. 65 , 298, (1999) Viral expression systems allow for the rapid production of large amounts of recombinant protein in cell culture. In particular, Sindbis virus vectors now exist that make possible the expression of a variety of heterologous proteins in mammalian culture system... |
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Induction of apoptosis by valinomycin: mitochondrial permeability transition causes intracellular acidification.
Cell Death Differ. 5 , 214, (1998) In order to determine whether disruption of mitochondrial function could trigger apoptosis in murine haematopoietic cells, we used the potassium ionophore valinomycin. Valinomycin induces apoptosis in the murine pre-B cell line BAF3, which cannot be inhibited... |
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Radioresistant Sf9 insect cells undergo an atypical form of Bax-dependent apoptosis at very high doses of γ-radiation.
Int. J. Radiat. Biol. 89(12) , 1017-27, (2013) To investigate the underlying mechanisms of cell-death at extremely high doses of radiation in radioresistant Spodoptera frugiperda-9 (Sf9) insect cells.Morphology, cell proliferation and DNA-fragmentation analysis was performed at 500-2000 Gy. Changes in int... |