Tamsolusin Hydrochloride

Tamsolusin Hydrochloride Structure
Tamsolusin Hydrochloride structure
Common Name Tamsolusin Hydrochloride
CAS Number 80223-99-0 Molecular Weight 444.97300
Density N/A Boiling Point 595.5ºC at 760 mmHg
Molecular Formula C20H29ClN2O5S Melting Point 230.6°C (lit.)
MSDS N/A Flash Point 313.9ºC

Inhibition of smooth muscle force generation by focal adhesion kinase inhibitors in the hyperplastic human prostate.

Am. J. Physiol. Renal Physiol. 307(7) , F823-32, (2014)

Smooth muscle contraction may be critical for lower urinary tract symptoms (LUTS) in patients with benign prostate hyperplasia and requires stable anchorage of the cytoskeleton to the cell membrane. These connections are regulated by focal adhesion kinase (FA...

Effects of alpha1-adrenoceptor antagonist (tamsulosin) on incident of ejaculation and semen quality in the goat.

Andrologia 47(3) , 354-9, (2015)

Male temporary contraception is occasionally required in some animals. Alpha1-adrenoceptor antagonist (tamsulosin) can cause ejaculation disorder. Two sets of Latin square were applied to six male goats to received either normal saline, dimethylsulphoxide or ...

Pharmacokinetic interaction of finasteride with tamsulosin hydrochloride: an open-label, randomized, 3-period crossover study in healthy Chinese male volunteers.

Clin. Ther. 37(2) , 462-72, (2015)

The primary aim of this study was to evaluate whether there was clinically significant pharmacokinetic (PK) interaction between finasteride and tamsulosin in healthy Chinese male subjects.This was an open-label, randomized, 3-period, crossover study. Subjects...

Release behaviour of single pellets and internal fine 3D structural features co-define the in vitro drug release profile.

AAPS J. 16(4) , 860-71, (2014)

Multi-pellet formulations are advantageous for the controlled release of drugs over single-unit dosage forms. To understand the diffusion controlled drug release mechanism, the pellet structure and drug release from a single pellet (not at dose level) were st...