Genistin
Genistin structure
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Common Name | Genistin | ||
|---|---|---|---|---|
| CAS Number | 529-59-9 | Molecular Weight | 432.378 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 788.9±60.0 °C at 760 mmHg | |
| Molecular Formula | C21H20O10 | Melting Point | 254ºC | |
| MSDS | Chinese USA | Flash Point | 280.7±26.4 °C | |
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Isoflavone pharmacokinetics and metabolism after consumption of a standardized soy and soy-almond bread in men with asymptomatic prostate cancer.
Cancer Prev. Res. (Phila.) 8 , 1045-54, (2015) Epidemiologic associations suggest that populations consuming substantial amounts of dietary soy exhibit a lower risk of prostate cancer. A 20-week randomized, phase II, crossover trial was conducted in 32 men with asymptomatic prostate cancer. The crossover ... |
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Membrane dipole modifiers modulate single-length nystatin channels via reducing elastic stress in the vicinity of the lipid mouth of a pore.
Biochim. Biophys. Acta 1848(1 Pt A) , 192-9, (2015) The polyene antifungal antibiotic nystatin confers its biological activity by forming pores in the membranes of target cells. Exposure of only one side of the membrane to nystatin is more relevant than two-side exposure because in vivo antibiotic molecules in... |
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Isoflavone extraction from okara using water as extractant.
Food Chem. 160 , 371-8, (2014) We here report on the use of water as a 'green' extraction solvent for the isolation of isoflavones from okara, a by-product of soymilk production. At a low liquid-to-solid ratio of 20 to 1 and 20 °C, 47% of the isoflavones that can be extracted with 70% aque... |
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An efficient and economical MTT assay for determining the antioxidant activity of plant natural product extracts and pure compounds.
J. Nat. Prod. 73 , 1193-5, (2010) Antioxidants scavenge free radicals, singlet oxygen, and electrons in cellular redox reactions. The yellow MTT [3-(4,5-dimethylthiazole-2-yl)-2,5-diphenyltetrazolium bromide] is reduced to a purple formazan by mitochondrial enzymes. NADPH is the basis of esta... |
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Antioxidant activity and anti-inflammatory activity of ethanol extract and fractions of Doenjang in LPS-stimulated RAW 264.7 macrophages.
Nutr. Res. Pract. 9 , 569-78, (2015) Fermentation can increase functional compounds in fermented soybean products, thereby improving antioxidant and/or anti-inflammatory activities. We investigated the changes in the contents of phenolics and isoflavones, antioxidant activity and anti-inflammato... |
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Enhancement of β-secretase inhibition and antioxidant activities of tempeh, a fermented soybean cake through enrichment of bioactive aglycones.
Pharm. Biol. 53(5) , 758-66, (2015) Soybean and its fermented products are the most common source of isoflavones in human food.The present study quantifies the major glycosides and aglycones in soybean and its fermented product tempeh isoflavone extracts. The comparision of antioxidant effects ... |
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Constituents of Dalbergia sissoo Roxb. leaves with osteogenic activity.
Bioorg. Med. Chem. Lett. 22 , 890-7, (2012) One new isoflavone glucoside, caviunin 7-O-[β-d-apiofuranosyl-(1→6)-β-d-glucopyranoside] (10) and a new itaconic derivative, (E)-4-methoxy-2-(3,4-dihydroxybenzylidene)-4-oxobutanoic acid (15) along with series of isoflavones and flavonols with their glucoside... |
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Effect of Monascus aged vinegar on isoflavone conversion in soy germ by soaking treatment.
Food Chem. 186 , 256-64, (2015) Soy germ rich in isoflavones has attracted much attention for health-promoting characteristics. An effective approach via Monascus aged vinegar soaking was adopted to enhance the aglycone amount. The profiles and interconversion of soy germ isoflavones via Mo... |
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High production of succinyl isoflavone glycosides by Bacillus licheniformis ZSP01 resting cells in aqueous miscible organic medium.
Biotechnol. Appl. Biochem. 62(2) , 255-9, (2015) To achieve efficient production of succinyldaidzin and succinylgenistin, resting cells of a solvent-stable strain Bacillus licheniformis ZSP01 were used to react with pure isoflavones or soybean flour extract in a reaction medium with 10% dimethyl sulfoxide. ... |
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Protective effects of germinated and fermented soybean extract against tert-butyl hydroperoxide-induced hepatotoxicity in HepG2 cells and in rats.
Food Funct. 6 , 3512-21, (2015) The aim of the current study is to investigate the antioxidant and hepatoprotective effects of germinated and fermented soybean extract (GFSE) on tert-butyl hydroperoxide (t-BHP)-induced oxidative stress in HepG2 cells and in the rat liver. High performance l... |