Osthole

Osthole Structure
Osthole structure
Common Name Osthole
CAS Number 484-12-8 Molecular Weight 244.286
Density 1.1±0.1 g/cm3 Boiling Point 396.7±42.0 °C at 760 mmHg
Molecular Formula C15H16O3 Melting Point 83-84°C
MSDS Chinese USA Flash Point 167.6±22.5 °C

[Effect of osthole on bone metabolism in rat femoral tissues in vitro].

Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 35(5) , 561-6, (2013)

To investigate the effect of osthole on bone metabolism in rat femoral tissues in vitro.The rat femoral tissues were isolated in vitro. The optimal concentrations of ostehole (1×10(-5) mol/L) and estradiol (1×10(-8) mol/L) (the positive control) were selected...

Osthole attenuates spinal cord ischemia–reperfusion injury through mitochondrial biogenesis–independent inhibition of mitochondrial dysfunction in rats

J. Surg. Res. 185(2) , 805-14, (2013)

Background Osthole, the main bioactive compounds isolated from the traditional Chinese medical herb broad Cnidium monnieri (L.) cusson, has been shown to exert spectrum of pharmacologic activities. The aim of this study was to investigate the potential neurop...

Osthole activates glucose uptake but blocks full activation in L929 fibroblast cells, and inhibits uptake in HCLE cells

Life Sci. 102(2) , 105-10, (2014)

Aims Osthole, a coumarin derivative, has been used in Chinese medicine and studies have suggested a potential use in treatment of diabetes and cancers. Therefore, we investigated the effects of osthole and other coumarins on GLUT1 activity in two cell lines t...